SCHEMBL23116646

SCHEMBL23116646

CC(C)CC1NCCc2c1n(C)c1ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.48
HTR2A P28223 1/20 0.46
HTR2C P28335 1/20 0.46
HSD17B10 Q99714 2/20 0.45
ALOX15 P16050 2/20 0.45
MAPK1 P28482 2/20 0.45
KDM4E B2RXH2 1/20 0.45
SLC6A4 P31645 1/20 0.43
MAOA P21397 4/20 0.39
MAOB P27338 1/20 0.39
HPGD P15428 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.35
GRIN2B Q13224 1/20 0.35
GPR3 P46089 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19786102 0.85 HTR2A (0.49) HTR2AHTR2CHSD17B10ALOX15MAPK1
SCHEMBL28060039 0.76 HTR2A (0.51) HTR2AHTR2CHSD17B10ALOX15MAPK1
SCHEMBL16299571 0.74 HTR2A (0.41) HTR2AHTR2CHSD17B10MAPK1KDM4E
SCHEMBL26836970 0.71 HTR2A (0.63) HTR2AHTR2CHSD17B10ALOX15MAPK1
SCHEMBL21883969 0.70 ABCB1 (0.45) HTR2AHTR2CHSD17B10ALOX15MAPK1
SCHEMBL18669422 0.70 GRIN2B (0.65) PRCPHTR2AHTR2CCYP2D6GRIN2B
SCHEMBL9880075 0.69 HTR2A (0.40) HTR2AHTR2CHSD17B10ALOX15MAPK1
SCHEMBL10686008 0.68 HTR2C (0.56) HTR2AHTR2CHSD17B10ALOX15MAPK1
SCHEMBL6644840 0.67 HTR2A (0.44) HTR2AHTR2CHSD17B10ALOX15MAPK1
SCHEMBL9880074 0.66 HTR2A (0.40) HTR2AHTR2CHSD17B10ALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630512-B2 Agents for differentiating stem cells and treating cancer MINERVA BIOTECHNOLOGIES CORPORATION (US) 2026-05-19 US disclosed
EP-3600451-B1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORP (US) 2025-12-24 EP disclosed
US-12202799-B2 Agents for differentiating stem cells and treating cancer MINERVA BIOTECHNOLOGIES CORPORATION (US) 2025-01-21 US disclosed
US-20240409515-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORPORATION 2024-12-12 US disclosed
US-20220242823-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORPORATION 2022-08-04 US disclosed
US-20220242823-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORPORATION 2022-08-04 US disclosed
US-20210299109-A1 AGENTS FOR TREATING CANCER AND METHODS FOR IDENTIFYING SAID AGENTS MINERVA BIOTECHNOLOGIES CORPORATION 2021-09-30 US disclosed
US-20210299109-A1 AGENTS FOR TREATING CANCER AND METHODS FOR IDENTIFYING SAID AGENTS MINERVA BIOTECHNOLOGIES CORPORATION 2021-09-30 US disclosed
US-20210087143-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORP (US) 2021-03-25 US disclosed
US-20210087143-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORP (US) 2021-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210299109-A1 AGENTS FOR TREATING CANCER AND METHODS FOR IDENTIFYING SAID AGENTS MCL1, CD44, EPCAM PRCP 2582/4885HTR2A 4615/4885HTR2C 4566/4885
US-12202799-B2 Agents for differentiating stem cells and treating cancer MCL1, CD44, CRABP2 PRCP 2373/4885HTR2A 4440/4885HTR2C 4453/4885
US-20210087143-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MCL1, CD44, CRABP2 PRCP 2373/4885HTR2A 4440/4885HTR2C 4453/4885
US-12630512-B2 Agents for differentiating stem cells and treating cancer MCL1, POU2F1, NES PRCP 1784/4885HTR2A 3307/4885HTR2C 1923/4885
US-20240409515-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MCL1, CD44, CRABP2 PRCP 2373/4885HTR2A 4440/4885HTR2C 4453/4885
US-20220242823-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MCL1, CD44, CRABP2 PRCP 2373/4885HTR2A 4440/4885HTR2C 4453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.