Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5340855 | 0.80 | TSHR (0.68) | TSHRPOLBCASP6LMNAMRGPRX4 | |
| SCHEMBL177424 | 0.80 | TSHR (0.83) | TSHRPOLBCASP6LMNAMRGPRX4 | |
| SCHEMBL29882038 | 0.80 | TSHR (0.83) | TSHRPOLBCASP6LMNAMRGPRX4 | |
| SCHEMBL4506502 | 0.79 | TSHR (0.66) | TSHRPOLBCASP6LMNAMRGPRX4 | |
| SCHEMBL28846281 | 0.78 | TSHR (0.69) | TSHRPOLBCASP6TTRLMNA | |
| SCHEMBL7089045 | 0.78 | TSHR (0.65) | TSHRPOLBCASP6TTRLMNA | |
| SCHEMBL23793741 | 0.78 | TSHR (0.64) | TSHRPOLBCASP6TTRLMNA | |
| SCHEMBL7009346 | 0.77 | TSHR (0.59) | TSHRPOLBCASP6TTRLMNA | |
| SCHEMBL825367 | 0.77 | TSHR (0.68) | TSHRPOLBCASP6TTRLMNA | |
| SCHEMBL701512 | 0.77 | TSHR (0.68) | TSHRPOLBCASP6LMNAMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579440-A | Triazolone compounds and uses thereof | INCEPTION 2 INC | 2016-05-11 | — | — | CN | disclosed |