SCHEMBL825367

SCHEMBL825367

CCOc1ccc(C(=O)O)cc1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.68
POLB P06746 2/20 0.57
CASP6 P55212 1/20 0.57
TTR P02766 2/20 0.56
PDE4A P27815 2/20 0.54
PDE4B Q07343 2/20 0.54
PDE4C Q08493 2/20 0.54
PDE4D Q08499 2/20 0.54
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA4 P22748 2/20 0.52
CA6 P23280 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
GAA P10253 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MAPT P10636 1/20 0.52
PTGS2 P35354 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28794951 0.87 NPC1 (0.67) TSHRPDE4APDE4BPDE4CPDE4D
SCHEMBL30597482 0.86 TSHR (0.68) TSHRPOLBCASP6CA12CA1
SCHEMBL384608 0.86 TSHR (0.68) TSHRPOLBCASP6CA12CA1
SCHEMBL29882038 0.85 TSHR (0.83) TSHRPOLBCASP6CA12CA1
SCHEMBL177424 0.85 TSHR (0.83) TSHRPOLBCASP6CA12CA1
SCHEMBL13693078 0.85 ALDH1A1 (0.59) TSHR
SCHEMBL10782030 0.85 ALDH1A1 (0.63) TSHR
SCHEMBL8790298 0.84 MAPK1 (0.69) TSHRPDE4APDE4BPDE4CPDE4D
SCHEMBL27919224 0.84 PDE4A (0.53) TSHRPOLBPDE4APDE4BPDE4C
SCHEMBL18655509 0.83 CA12 (0.61) TSHRPOLBPDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637574-B2 Coating composition KANSAI PAINT CO., LTD. (JP) 2026-05-26 US disclosed
US-12576431-B2 Method for forming multi-layer coating film KANSAI PAINT CO., LTD. (JP) 2026-03-17 US disclosed
EP-4692260-A1 KIT FOR THREE-COMPONENT COATING COMPOSITION, THREE-COMPONENT COATING COMPOSITION, AND IN-MOLD COATING METHOD Kansai Paint Co., Ltd (JP) 2026-02-11 EP disclosed
US-20260035593-A1 AQUEOUS COATING MATERIAL COMPOSITION, METHOD FOR FORMING COATING FILM, AND METHOD FOR FORMING MULTILAYER COATING FILM KANSAI PAINT CO LTD (JP) 2026-02-05 US disclosed
US-12534635-B2 Aqueous coating composition KANSAI PAINT CO., LTD. (JP) 2026-01-27 US disclosed
US-20260021615-A1 COATING COMPOSITION AND IN-MOLD COATING METHOD KANSAI PAINT CO LTD (JP) 2026-01-22 US disclosed
US-12485593-B2 Method for forming in-mold coating multi-layer coating film KANSAI PAINT CO., LTD. (JP) 2025-12-02 US disclosed
EP-4653500-A1 THERMOSETTING RESIN COMPOSITION AND CURED FILM Kyoeisha Chemical Co., Ltd. (JP) 2025-11-26 EP disclosed
US-12466978-B2 Nanocellulose-containing aqueous coating composition for automotive exterior KANSAI PAINT CO., LTD. (JP) 2025-11-11 US disclosed
EP-4245830-B1 LUBRICANT BASE OIL KAO CORP (JP) 2025-09-10 EP disclosed
US-20090252879-A1 Aqueous coating composition KANSAI PAINT CO., LTD. 2009-10-08 US disclosed
US-20090075063-A1 Automobile water-based paint KANSAI PAINT CO., LTD. (JP) 2009-03-19 US disclosed
US-20080268269-A1 Production method of pigment-dispersing resin KANSAI PAINT CO., LTD. (JP) 2008-10-30 US disclosed
US-20080199625-A1 Colored coating composition KANSAI PAINT CO., LTD. (JP) 2008-08-21 US disclosed
CN-101209446-A Multi-layer coating film forming method KANSAI PAINT CO LTD (JP) 2008-07-02 CN disclosed
US-20080108743-A1 a hydroxy-containing acrylic or polyester resin, a melamine resin; and a polyoxyethylene glycol diester compound for excellent distinctness of image, appearance, and water resistance; multilayer topcoat film clear coat for automobiles KANSAI PAINT CO., LTD. (JP) 2008-05-08 US disclosed
WO-2008044583-A1 AQUEOUS METALLIC COATING COMPOSITION AND METHOD FOR FORMING A MULTILAYER COATING FILM KANSAI PAINT CO., LTD. (JP) 2008-04-17 WO disclosed
US-3985797-A Hydroxylation of aromatic compounds UOP INC. (US) 1976-10-12 US disclosed
US-3985796-A Hydroxylation of aromatic compounds UOP INC. (US) 1976-10-12 US disclosed
US-3931295-A Hydroxylation of aromatic compounds UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637574-B2 Coating composition ITGB3, ATG13, C9 TSHR 3554/4885POLB 2215/4885CASP6 3261/4885
US-12576431-B2 Method for forming multi-layer coating film SPIN3, SLC6A3, MARK3 TSHR 3810/4885POLB 2150/4885CASP6 3182/4885
US-20260035593-A1 AQUEOUS COATING MATERIAL COMPOSITION, METHOD FOR FORMING COATING FILM, AND METHOD FOR FORMING MULTILAYER COATING FILM COL2A1, ALKBH2, C9 TSHR 4648/4885POLB 2347/4885CASP6 3758/4885
US-20260021615-A1 COATING COMPOSITION AND IN-MOLD COATING METHOD VIM, VCL, C9 TSHR 4857/4885POLB 3137/4885CASP6 3463/4885
US-12534635-B2 Aqueous coating composition BMI1, PNMT, EED TSHR 1628/4885POLB 1862/4885CASP6 3984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.