Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28060106 | 0.89 | GLRA1 (0.60) | GLRA1LMNAHPGDALDH1A1FFAR1 | |
| SCHEMBL28060142 | 0.89 | GLRA1 (0.60) | GLRA1LMNAHPGDALDH1A1FFAR1 | |
| SCHEMBL28060114 | 0.89 | GLRA1 (0.60) | GLRA1LMNAHPGDALDH1A1FFAR1 | |
| SCHEMBL28060109 | 0.86 | GLRA1 (0.58) | GLRA1LMNAHPGDALDH1A1FFAR1 | |
| SCHEMBL28078446 | 0.85 | GLRA1 (0.60) | GLRA1LMNAHPGDALDH1A1MAOB | |
| SCHEMBL26908057 | 0.81 | GLRA1 (0.57) | GLRA1LMNAHPGDALDH1A1FFAR1 | |
| SCHEMBL128058 | 0.80 | GLRA1 (0.57) | GLRA1LMNAHPGDALDH1A1FFAR1 | |
| SCHEMBL26908068 | 0.80 | GLRA1 (0.56) | GLRA1LMNAHPGDALDH1A1FFAR1 | |
| SCHEMBL16860746 | 0.79 | GLRA1 (1.00) | GLRA1LMNAHPGDALDH1A1THRA | |
| SCHEMBL28060081 | 0.78 | GLRA1 (0.55) | GLRA1LMNAHPGDALDH1A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384608-B | A kind of cumene amphyl and preparation method thereof | 四川海思科制药有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-105384608-A | Isopropyl-phenol derivative and preparation method therefor | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2016-03-09 | — | — | CN | disclosed |