SCHEMBL128058

SCHEMBL128058

CC(C)c1cccc(C(=O)O)c1OCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GLRA1 P23415 2/20 0.57
PTGER1 P34995 1/20 0.49
ALDH1A1 P00352 1/20 0.46
CTSV O60911 1/20 0.44
CTSL P07711 1/20 0.44
LMNA P02545 1/20 0.43
HPGD P15428 1/20 0.43
NR4A2 P43354 2/20 0.43
FFAR1 O14842 2/20 0.43
MRGPRX4 Q96LA9 2/20 0.43
NR4A1 P22736 1/20 0.43
NR4A3 Q92570 1/20 0.43
FOLH1 Q04609 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26908096 0.90 GLRA1 (0.56) GLRA1PTGER1ALDH1A1LMNAHPGD
SCHEMBL8408603 0.87 ALDH1A1 (0.54) GLRA1ALDH1A1LMNAHPGDKMT2A
SCHEMBL21338330 0.87 ALDH1A1 (0.47) GLRA1PTGER1ALDH1A1CTSVCTSL
SCHEMBL28616880 0.84 KMT2A (0.43) ALDH1A1LMNAHPGDMEN1KMT2A
SCHEMBL15716510 0.84 ALDH1A1 (0.58) PTGER1ALDH1A1CTSVCTSLLMNA
SCHEMBL28078446 0.84 GLRA1 (0.60) GLRA1ALDH1A1LMNAHPGD
SCHEMBL28061345 0.84 GLRA1 (0.50) GLRA1PTGER1ALDH1A1LMNAHPGD
SCHEMBL28060114 0.82 GLRA1 (0.60) GLRA1ALDH1A1LMNAHPGDFFAR1
SCHEMBL28060142 0.82 GLRA1 (0.60) GLRA1ALDH1A1LMNAHPGDFFAR1
SCHEMBL28060106 0.82 GLRA1 (0.60) GLRA1ALDH1A1LMNAHPGDFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1866033-B1 SUNSCREEN AEROSOL SPRAY ENSIGN LABORATORIES PTY LTD (AU) 2017-04-19 EP claimed
EP-1594454-B1 FILM FORMING HYDROALCOHOLIC FOAM STIEFEL RES AUSTRALIA PTY LTD (AU) 2016-07-27 EP claimed
EP-1595936-B1 COMPOSITION FOR EXTERNAL USE VITAMIN C60 BIORES CORP (JP) 2011-10-19 EP claimed
US-7691403-B2 Non-absorbent tampon containing additives inhibiting TSST-1 KIMBERLY-CLARK WORLDWIDE, INC. (US) 2010-04-06 US claimed
EP-1641443-B1 COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING DIMTHYLSULPHONE AND A SUNSCREEN FOR THE CURE AND PREVENTION OF IRRITATION, INFLAMMATION AND CUTANEOUS ERYTHEMA DE PAOLI AMBROSI GIANFRANCO (IT) 2009-01-14 EP claimed
US-20080096850-A1 Exposing Grampositive bacteria of vagina to a synergistic mixture including hexachlorophene, benzyl paraben, benzyl salicylate, a benzophenone, chlorophene, 2,4-diaminodiphenylamine, dichlorophene, HC Green No. 1, HC Orange No. 1, HC Red No. 1, isopropylbenzyl salicylate, and phenyl salicylate; tampons KIMBERLY-CLARK WORLDWIDE, INC. (US) 2008-04-24 US claimed
US-7118759-B2 Absorbent articles containing additives KIMBERLY-CLARK WORLDWIDE, INC. (US) 2006-10-10 US claimed
US-20030165559-A1 Non-absorbent articles containing additives KIMBERLY-CLARK WORLDWIDE, INC. 2003-09-04 US claimed
US-20030158156-A1 Methods for inhibiting the production of TSST-1 KIMBERLY-CLARK WORLDWIDE, INC. 2003-08-21 US claimed
US-20030157149-A1 Menstrual tampons comprising cerulenin, triclosan, or hexachlorophene to inhibit production of toxic shock syndrome toxins by gram-positive bacteria KIMBERLY-CLARK WORLDWIDE, INC. 2003-08-21 US claimed
US-11585750-B2 Arrangement for determining body surface properties by means of Multiple Spatially Resolved Reflection Spectroscopy (MSRRS) HENKEL AG & CO. KGAA (DE) 2023-02-21 US disclosed
US-20200300754-A1 ARRANGEMENT FOR DETERMINING BODY SURFACE PROPERTIES BY MEANS OF MULTIPLE SPATIALLY RESOLVED REFLECTION SPECTROSCOPY (MSRRS) HENKEL AG & CO. KGAA (DE) 2020-09-24 US disclosed
EP-3707725-A1 ARRANGEMENT FOR DETERMINING BODY SURFACE PROPERTIES BY MEANS OF MULTIPLE SPATIALLY RESOLVED REFLECTION SPECTROSCOPY (MSRRS) Henkel AG & Co. KGaA (DE) 2020-09-16 EP disclosed
EP-3106147-B1 METHOD FOR PRODUCING POLYMERS OF ACRYLOYLDIMETHYL TAURATE, NEUTRAL MONOMERS, MONOMERS WITH CARBOXYLIC ACIDS AND SPECIAL CROSSLINKING AGENTS CLARIANT INT LTD (CH) 2019-09-04 EP disclosed
EP-3217981-B1 COSMETIC COMPOSITION, ITS PROPHYLACTIC USE AND IN TREATMENT OF SKIN IMPURITIES, OF SKIN SUSCEPTIBLE TO ACNE AND ACNE Cosmedes GmbH (DE) 2019-07-31 EP disclosed
US-5744062-A CONTROLLING VISCOSITY R.I.T.A. CORPORATION (US) 1998-04-28 US disclosed
WO-1998008597-A1 EMULSIFIER BLENDS FOR OIL-IN-WATER EMULSIONS R.I.T.A. CORPORATION (US) 1998-03-05 WO disclosed
WO-1998005294-A1 AN OIL-IN-WATER EMULSION FOR USE ON HUMAN SKIN FOR CLEANSING, PRESERVING OR IMPROVING THE CONDITION OF THE SKIN PLUM KEMI PRODUKTION A/S (DK) 1998-02-12 WO disclosed
EP-0778821-A1 ORTHO-SUBSTITUTED AROMATIC ETHER COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR PAIN RELIEF ZENECA LIMITED (GB) 1997-06-18 EP disclosed
WO-1996006822-A1 ORTHO-SUBSTITUTED AROMATIC ETHER COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR PAIN RELIEF ZENECA LIMITED (GB) 1996-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080096850-A1 Exposing Grampositive bacteria of vagina to a synergistic mixture including hexachlorophene, benzyl paraben, benzyl salicylate, a benzophenone, chlorophene, 2,4-diaminodiphenylamine, dichlorophene, HC Green No. 1, HC Orange No. 1, HC Red No. 1, isopropylbenzyl salicylate, and phenyl salicylate; tampons TST, DDT, SULT1E1 GLRA1 2113/4885PTGER1 823/4885ALDH1A1 387/4885
US-20030158156-A1 Methods for inhibiting the production of TSST-1 TST, TSSK1B, DNTT GLRA1 2581/4885PTGER1 3201/4885ALDH1A1 3495/4885
US-20030165559-A1 Non-absorbent articles containing additives CNOT1, DCUN1D1, CNDP2 GLRA1 2905/4885PTGER1 3765/4885ALDH1A1 3289/4885
US-20030157149-A1 Menstrual tampons comprising cerulenin, triclosan, or hexachlorophene to inhibit production of toxic shock syndrome toxins by gram-positive bacteria TPSAB1, TPT1, TST GLRA1 4103/4885PTGER1 1522/4885ALDH1A1 3909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.