Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28060195 | 0.85 | XDH (0.41) | XDHIDO1TDO2PTGDR2MEN1 | |
| SCHEMBL16347425 | 0.84 | XDH (0.49) | XDHIDO1TDO2PTGDR2MEN1 | |
| SCHEMBL16388293 | 0.82 | IDO1 (0.41) | XDHIDO1TDO2PTGDR2MEN1 | |
| SCHEMBL28827071 | 0.80 | XDH (0.43) | XDHIDO1TDO2PTGDR2MEN1 | |
| SCHEMBL16347042 | 0.78 | XDH (0.37) | XDHIDO1TDO2PTGDR2MEN1 | |
| SCHEMBL25252586 | 0.71 | NR1H2 (0.43) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL7825992 | 0.67 | PDE4A (0.48) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL28060125 | 0.67 | XDH (0.43) | XDHIDO1TDO2PTGDR2MEN1 | |
| SCHEMBL16347282 | 0.66 | XDH (0.51) | XDHIDO1TDO2PTGDR2MEN1 | |
| SCHEMBL28815520 | 0.65 | SLC16A3 (0.51) | SMN1; SMN2LMNAFAAHCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105492429-A | Heteroaryl inhibitors of SUMO activating enzyme | MILLENNIUM PHARM INC | 2016-04-13 | — | — | CN | disclosed |