Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | CPS1 | P31327 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2720566 | 0.84 | CYP1A2 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29641932 | 0.84 | CYP1A2 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1017145 | 0.80 | CYP11B1 (0.47) | — | |
| SCHEMBL30079514 | 0.80 | CYP11B1 (0.47) | — | |
| SCHEMBL6212996 | 0.80 | CPS1 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16959354 | 0.80 | CA12 (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31119234 | 0.78 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6196567 | 0.78 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29870653 | 0.77 | GPR3 (0.42) | CYP1A2 | |
| SCHEMBL26426439 | 0.77 | GPR3 (0.42) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105492429-A | Heteroaryl inhibitors of SUMO activating enzyme | MILLENNIUM PHARM INC | 2016-04-13 | — | — | CN | disclosed |