1,4-Butanediol

1,4-Butanediol

SCHEMBL28060381

CC=C(C)C(=O)O.OCCCCO.OCCCCO

nearest known ligand 0.40

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.40
FFAR1 O14842 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
CAMK2A Q9UQM7 1/20 0.38
FNTA P49354 1/20 0.35
FNTB P49356 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
HSD17B10 Q99714 1/20 0.33
PTGS1 P23219 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
AKR1C3 P42330 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL1326105 1.00 GPR84 (0.40) GPR84FFAR1FFAR4CAMK2AFNTA
SCHEMBL28172732 0.97 GPR84 (0.44) GPR84FFAR1FFAR4CAMK2AFNTA
SCHEMBL28117609 0.97 GPR84 (0.44) GPR84FFAR1FFAR4CAMK2AFNTA
1,6-Hexanediol SCHEMBL1602597 0.97 GPR84 (0.44) GPR84FFAR1FFAR4CAMK2AFNTA
1,5-Pentanediol SCHEMBL6315956 0.97 GPR84 (0.44) GPR84FFAR1FFAR4CAMK2AFNTA
1,5-Pentanediol SCHEMBL27278415 0.97 GPR84 (0.44) GPR84FFAR1FFAR4CAMK2AFNTA
SCHEMBL3911767 0.97 GPR84 (0.44) GPR84FFAR1FFAR4CAMK2AFNTA
SCHEMBL5605452 0.97 GPR84 (0.44) GPR84FFAR1FFAR4CAMK2AFNTA
SCHEMBL16505621 0.97 GPR84 (0.44) GPR84FFAR1FFAR4CAMK2AFNTA
1,3-Propanediol SCHEMBL1979203 0.95 CAMK2A (0.38) GPR84FFAR1FFAR4CAMK2AFNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109020809-A A kind of preparation method of 1,4-butanediol dimethylacrylate 南京林业大学 2018-12-18 CN disclosed
CN-105829079-A A method for coating and a coated surface, a coating and an implant containing such coating 斯卡勒植入物公司 2016-08-03 CN disclosed