Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 15/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16670082 | 0.83 | SSTR5 (0.38) | SSTR5TSHRSSTR1HRH2KCNH2 | |
| SCHEMBL16670601 | 0.81 | SSTR5 (0.39) | SSTR5TSHRSSTR1HRH2KCNH2 | |
| SCHEMBL28060613 | 0.78 | HRH2 (0.36) | SSTR5SSTR1HRH2 | |
| SCHEMBL16616058 | 0.77 | SSTR5 (0.34) | SSTR5TSHRSSTR1KCNH2 | |
| SCHEMBL16670319 | 0.77 | KDM4E (0.36) | SSTR5 | |
| SCHEMBL16669602 | 0.74 | ALDH1A1 (0.41) | SSTR5TSHRHRH2 | |
| SCHEMBL16670329 | 0.71 | MEN1 (0.40) | SSTR5HRH2 | |
| SCHEMBL16670334 | 0.71 | SSTR5 (0.51) | SSTR5KCNH2 | |
| SCHEMBL16683346 | 0.70 | SSTR5 (0.44) | SSTR5KCNH2 | |
| SCHEMBL16624248 | 0.70 | SSTR5 (0.34) | SSTR5SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612158-A | Antagonists of somatostatin receptor subtype 5 (sstr5) | TAKEDA PHARMACEUTICALS CO | 2016-05-25 | — | — | CN | disclosed |