Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL653644 | 0.85 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL17292769 | 0.82 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL1649995 | 0.81 | ALDH1A1 (0.41) | HPGDALDH1A1CYP3A4ZDHHC7FDPS | |
| SCHEMBL8162799 | 0.80 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL1897662 | 0.80 | TSHR (0.76) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL729433 | 0.80 | TSHR (0.76) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL17851220 | 0.80 | TSHR (0.76) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL731354 | 0.80 | TSHR (0.76) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL17851227 | 0.80 | TSHR (0.76) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL731397 | 0.80 | TSHR (0.76) | TSHRHPGDALDH1A1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105434179-A | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS | CHARITE UNIV BE | 2016-03-30 | — | — | CN | claimed |
| CN-105434179-A | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS | CHARITE UNIV BE | 2016-03-30 | — | — | CN | disclosed |