Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | PPARG | P37231 | 7/20 | 0.55 |
| ▸ | PPARD | Q03181 | 7/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249203 | 0.97 | NOD1 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL15047640 | 0.97 | NOD1 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL3249208 | 0.97 | NOD1 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL29978075 | 0.97 | NOD1 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL29977697 | 0.97 | NOD1 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL28184751 | 0.97 | NOD1 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hydrochloric Acid SCHEMBL5034548 | 0.95 | NOD1 (0.55) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL3802336 | 0.95 | NOD1 (0.54) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL3802334 | 0.95 | NOD1 (0.54) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL24712636 | 0.90 | NOD1 (0.51) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103338745-B | Skin external preparation and production method thereof | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2016-06-01 | — | — | CN | disclosed |