⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801341 | 0.97 | — | — | |
| SCHEMBL996580 | 0.65 | — | — | |
| SCHEMBL691231 | 0.62 | MGLL (0.33) | — | |
| SCHEMBL2010672 | 0.62 | MGLL (0.33) | — | |
| SCHEMBL7850697 | 0.60 | — | — | |
| SCHEMBL529229 | 0.59 | — | — | |
| SCHEMBL28587188 | 0.59 | — | — | |
| SCHEMBL8781897 | 0.59 | — | — | |
| SCHEMBL9717997 | 0.59 | — | — | |
| SCHEMBL6635004 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021043187-A1 | METHOD FOR PREPARING BORON SALT OF DIPEPTIDE OF VALINE-PROLINE | 上海馨远医药科技有限公司 | 2021-03-11 | — | — | WO | claimed |
| CN-110452258-B | Preparation method of dipeptide valine boron proline salt | 上海馨远医药科技有限公司 | 2021-01-01 | — | — | CN | claimed |
| US-7115650-B1 | Compositions for improving fertility | FERRING BV (NL) | 2006-10-03 | — | — | US | claimed |
| CN-115943312-A | Biomarker ANTXR1 of immunosuppressive fibroblast population and its use in predicting response to immunotherapy | 法国居里学院 | 2023-04-07 | — | — | CN | disclosed |
| WO-2021043187-A1 | METHOD FOR PREPARING BORON SALT OF DIPEPTIDE OF VALINE-PROLINE | 上海馨远医药科技有限公司 | 2021-03-11 | — | — | WO | disclosed |
| CN-110452258-B | Preparation method of dipeptide valine boron proline salt | 上海馨远医药科技有限公司 | 2021-01-01 | — | — | CN | disclosed |
| CN-102286011-B | Pyrrolidine botonate ester depeptidyl peptidase inhibitors and its pharmaceutical composition | 美德（江西）生物科技有限公司 | 2017-10-03 | — | — | CN | disclosed |
| CN-101522201-B | The solid citrate of DPP-IV inhibitor and tartrate | HANGZHOU HUADONG MEDICINE GROUP PHARMACEUTICAL RESEARCH INSTITUTE Co.,Ltd. (CN) | 2015-08-19 | — | — | CN | disclosed |
| US-8299271-B2 | Solid tartrate salts of DPP-IV inhibitors | PHENOMIX CORPORATION (US) | 2012-10-30 | — | — | US | disclosed |
| CN-102286011-A | Pyrrolidine botonate ester dipeptidyl peptidase inhibitor and its pharmaceutical composition | — | 2011-12-21 | — | — | CN | disclosed |
| US-20100323988-A1 | SOLID CITRATE AND TARTRATE SALTS OF DPP-IV INHIBITORS | PHENOMIX CORPORATION (US) | 2010-12-23 | — | — | US | disclosed |
| EP-1282600-A1 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | Ferring BV (NL) | 2003-02-12 | — | — | EP | disclosed |
| EP-1280797-A1 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | FERRING B.V. (NL) | 2003-02-05 | — | — | EP | disclosed |
| WO-2003000250-A1 | 3-FLUORO-PYRROLIDINES AS ANTIDIABETIC AGENTS | FERRING BV (NL) | 2003-01-03 | — | — | WO | disclosed |
| EP-1171121-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIPEPTIDYLPEPTIDASE IV INHIBITORS FOR THE PROMOTION OF GROWTH | FERRING B.V. (NL) | 2002-01-16 | — | — | EP | disclosed |
| EP-1162969-A2 | COMPOSITIONS FOR IMPROVING FERTILITY | Ferring BV (NL) | 2001-12-19 | — | — | EP | disclosed |
| WO-2001081337-A1 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | FERRING B.V. (NL) | 2001-11-01 | — | — | WO | disclosed |
| WO-2001081304-A1 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | FERRING BV (NL) | 2001-11-01 | — | — | WO | disclosed |
| WO-2000056296-A2 | COMPOSITIONS FOR IMPROVING FERTILITY | FERRING BV (NL) | 2000-09-28 | — | — | WO | disclosed |
| WO-2000056297-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIPEPTIDY PEPTIDASE IV INHIBITORS FOR THE PROMOTION OF GROWTH | FERRING B.V. (NL) | 2000-09-28 | — | — | WO | disclosed |