Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30198446 | 0.78 | CYP1A2 (0.60) | KDM4EALDH1A1HPGDMAPTRECQL | |
| SCHEMBL1672650 | 0.78 | CYP1A2 (0.60) | KDM4EALDH1A1HPGDMAPTRECQL | |
| SCHEMBL30527184 | 0.78 | CYP1A2 (0.60) | KDM4EALDH1A1HPGDMAPTRECQL | |
| SCHEMBL13911016 | 0.74 | CYP1A2 (0.56) | KDM4EALDH1A1HPGDMAPTRECQL | |
| SCHEMBL27580222 | 0.74 | CYP1A2 (0.53) | KDM4EALDH1A1HPGDMAPTRECQL | |
| SCHEMBL28433752 | 0.73 | ADORA2A (0.44) | KDM4EALDH1A1POLBTDP1HPGD | |
| SCHEMBL30147995 | 0.72 | ADRA2A (0.50) | KDM4EALDH1A1HPGDMAPTPKM | |
| SCHEMBL16446611 | 0.72 | ADRA2A (0.50) | KDM4EALDH1A1HPGDMAPTPKM | |
| SCHEMBL9352344 | 0.72 | POLB (0.46) | KDM4EALDH1A1POLBTDP1HPGD | |
| SCHEMBL11845974 | 0.71 | GGPS1 (0.44) | KDM4EALDH1A1POLBTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530186-A | Synthesis method of quinazoline derivative | 多氟多新材料股份有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-117229222-A | Method for synthesizing quinazoline by dehydrogenation of tetrahydroquinazoline | 西安石油大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-110291066-B | Compound and organic electroluminescent element comprising same | 株式会社LG化学（KR） | 2023-01-13 | — | — | CN | disclosed |
| CN-112941549-A | Synthetic method of quinazoline derivative, benzoxazine derivative and benzothiazole derivative | 石河子大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-108264489-B | Method for synthesizing quinazoline in water | 南京理工大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-108264489-A | A kind of method for synthesizing quinazoline in water | 南京理工大学 | 2018-07-10 | — | — | CN | disclosed |
| CN-103772371-B | 6-furyl quinazoline-4-amines and its production and use | 复旦大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-103772411-B | Sulfur-bearing 6-furyl quinazoline-4-amines and its production and use | 复旦大学 | 2016-08-03 | — | — | CN | disclosed |