Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20024208 | 0.97 | TSHR (0.52) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL334658 | 0.92 | — | — | |
| SCHEMBL30341 | 0.92 | — | — | |
| SCHEMBL334659 | 0.92 | — | — | |
| SCHEMBL27747621 | 0.90 | TSHR (0.61) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| Methane SCHEMBL11336685 | 0.89 | — | — | |
| Methoxymethane SCHEMBL1074158 | 0.89 | TSHR (0.59) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL16809957 | 0.89 | ALDH1A1 (0.50) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL20024210 | 0.87 | TSHR (0.44) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL3660412 | 0.86 | ALDH1A1 (0.48) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622802-B | Catalytic component, catalyst for ethylene polymerization and preparation method thereof | 中国石油化工股份有限公司 | 2017-12-19 | — | — | CN | claimed |
| CN-105622802-A | Catalyst component for ethylene polymerization reaction, catalyst, and preparation method of catalyst component | CHINA PETROLEUM & CHEM CORP | 2016-06-01 | — | — | CN | claimed |
| CN-105622802-B | Catalytic component, catalyst for ethylene polymerization and preparation method thereof | 中国石油化工股份有限公司 | 2017-12-19 | — | — | CN | disclosed |
| CN-105622802-A | Catalyst component for ethylene polymerization reaction, catalyst, and preparation method of catalyst component | CHINA PETROLEUM & CHEM CORP | 2016-06-01 | — | — | CN | disclosed |