Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 2/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185795 | 0.79 | JAK1 (0.39) | JAK1JAK3JAK2 | |
| Hydrochloric Acid SCHEMBL2805240 | 0.78 | JAK1 (0.38) | JAK1JAK3JAK2 | |
| SCHEMBL2806133 | 0.76 | JAK1 (0.32) | JAK1JAK3JAK2 | |
| SCHEMBL2808729 | 0.71 | PTGS2 (0.38) | JAK1JAK3JAK2 | |
| SCHEMBL2808733 | 0.71 | PTGS2 (0.38) | JAK1JAK3JAK2 | |
| SCHEMBL27870363 | 0.69 | PTGS2 (0.42) | JAK1JAK3JAK2 | |
| SCHEMBL2806973 | 0.67 | PTGS2 (0.44) | JAK1JAK3JAK2 | |
| SCHEMBL2839198 | 0.67 | FLT4 (0.37) | JAK1JAK3JAK2 | |
| SCHEMBL27870364 | 0.67 | PTGS2 (0.37) | JAK1JAK3JAK2 | |
| SCHEMBL185826 | 0.65 | PTGS2 (0.41) | JAK1JAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131075-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-05-23 | — | — | US | disclosed |
| US-20100240669-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131075-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | JAK1 936/4885JAK3 2297/4885JAK2 1802/4885 |
| US-20100240669-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | JAK1 936/4885JAK3 2297/4885JAK2 1802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.