Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892950 | 0.81 | PTPN1 (0.43) | RECQLPTPN1ROCK2ROCK1FFAR4 | |
| SCHEMBL893097 | 0.80 | PTPN1 (0.46) | PTPN1NPSR1ALDH1A1LMNATSHR | |
| SCHEMBL308869 | 0.78 | PTPN1 (0.59) | PTPN1ROCK2ROCK1NOTUMKMT2A | |
| SCHEMBL11747518 | 0.77 | FFAR4 (0.42) | PTPN1FFAR4NOTUMKMT2A | |
| SCHEMBL19339952 | 0.76 | NPSR1 (0.43) | RECQLNPSR1KMT2AHSP90AA1HTT | |
| SCHEMBL892655 | 0.75 | PTPN1 (0.53) | RECQLPTPN1KMT2AHTTUSP30 | |
| SCHEMBL25328929 | 0.75 | NPSR1 (0.42) | RECQLROCK2NPSR1KMT2AHSP90AA1 | |
| SCHEMBL1137236 | 0.74 | PTPN1 (0.52) | RECQLPTPN1ROCK2NOTUMKMT2A | |
| SCHEMBL892180 | 0.74 | PTPN1 (0.52) | RECQLPTPN1ROCK2ROCK1NOTUM | |
| SCHEMBL6936690 | 0.74 | PTPN1 (0.52) | PTPN1ROCK2ROCK1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803252-B | Be used for the treatment of indole amides derivative and the related compound thereof of neurodegenerative disorders | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2016-05-25 | — | — | CN | disclosed |