Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28061526 | 0.91 | S1PR2 (0.36) | S1PR2S1PR1S1PR3LPAR2KMT2A | |
| SCHEMBL15220339 | 0.78 | MAPT (0.38) | S1PR2S1PR1S1PR3LPAR2KMT2A | |
| SCHEMBL8417929 | 0.76 | KMT2A (0.49) | KMT2AMEN1MAPTL3MBTL1LMNA | |
| SCHEMBL10348382 | 0.74 | MAPT (0.51) | KMT2AMEN1MAPTL3MBTL1LMNA | |
| SCHEMBL10348410 | 0.74 | MAPT (0.51) | KMT2AMEN1MAPTL3MBTL1LMNA | |
| SCHEMBL10348443 | 0.74 | MAPT (0.51) | KMT2AMEN1MAPTL3MBTL1LMNA | |
| SCHEMBL10348444 | 0.74 | MAPT (0.51) | KMT2AMEN1MAPTL3MBTL1LMNA | |
| SCHEMBL10348383 | 0.74 | MAPT (0.51) | KMT2AMEN1MAPTL3MBTL1LMNA | |
| SCHEMBL10349008 | 0.74 | MAPT (0.51) | KMT2AMEN1MAPTL3MBTL1LMNA | |
| SCHEMBL27986524 | 0.74 | S1PR2 (0.36) | S1PR2S1PR1S1PR3LPAR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105906617-A | Modulators of HEC1 activity and methods thereof | 泰纬生命科技股份有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-103038231-B | Modulators of HEC1 activity and methods thereof | Taivex Therapeutics Corp. (CN) | 2016-04-20 | — | — | CN | disclosed |