Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | EDNRB | P24530 | 2/20 | 0.37 |
| ▸ | EDNRA | P25101 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2805537 | 0.91 | SERPINE1 (0.46) | SERPINE1MEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL2805766 | 0.88 | SERPINE1 (0.45) | SERPINE1MEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL2805777 | 0.87 | SERPINE1 (0.42) | SERPINE1MEN1ALDH1A1KMT2APPARG | |
| SCHEMBL2808105 | 0.87 | SERPINE1 (0.43) | SERPINE1MEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL2807928 | 0.84 | KDM4E (0.44) | SERPINE1MEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL2808191 | 0.81 | SERPINE1 (0.45) | SERPINE1MEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL2806589 | 0.81 | SERPINE1 (0.43) | SERPINE1MEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL13168276 | 0.81 | PIN1 (0.42) | SERPINE1MEN1ALDH1A1KMT2APPARG | |
| SCHEMBL2810186 | 0.80 | SERPINE1 (0.54) | SERPINE1MEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL2807914 | 0.80 | SERPINE1 (0.54) | SERPINE1MEN1ALDH1A1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240642-A1 | 1H-Indole-2-Carboxylic Acid Derivatives Useful As PPAR Modulators | SMITHKLINE BEECHAM CORPORATION (US) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240642-A1 | 1H-Indole-2-Carboxylic Acid Derivatives Useful As PPAR Modulators | PPARD, PPARA, PPARG | SERPINE1 4215/4885MEN1 4809/4885ALDH1A1 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.