SCHEMBL28061836

SCHEMBL28061836

O=C(O)OC(=O)c1ccccc1.[NaH]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.61
F2 P00734 1/20 0.61
TSHR P16473 6/20 0.56
TDP1 Q9NUW8 4/20 0.50
TP53 P04637 1/20 0.50
PLA2G7 Q13093 1/20 0.48
ALDH1A1 P00352 4/20 0.48
KMT2A Q03164 3/20 0.48
MAPT P10636 3/20 0.48
POLB P06746 2/20 0.48
MAPK1 P28482 1/20 0.48
HIF1A Q16665 1/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A3 Q01959 1/20 0.48
CES2 O00748 2/20 0.48
CES1 P23141 2/20 0.48
DAO P14920 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
HSD17B10 Q99714 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4260982 0.97 LMNA (0.64) LMNAF2TSHRTDP1TP53
SCHEMBL27955112 0.95 LMNA (0.61) LMNAF2TSHRTDP1TP53
SCHEMBL28180893 0.93 LMNA (0.58) LMNAF2TSHRTDP1TP53
SCHEMBL27906383 0.91 LMNA (0.56) LMNAF2TSHRTDP1TP53
SCHEMBL431406 0.90 LMNA (0.67) LMNAF2TSHRTDP1TP53
SCHEMBL2591454 0.90 LMNA (0.67) LMNAF2TSHRTDP1TP53
SCHEMBL16440015 0.87 LMNA (0.64) LMNAF2TSHRTDP1TP53
SCHEMBL27863223 0.87 LMNA (0.48) LMNAF2TSHRTDP1TP53
SCHEMBL52413 0.87 LMNA (0.70) LMNAF2TSHRTDP1TP53
Benzene SCHEMBL27793442 0.87 LMNA (0.70) LMNAF2TSHRTDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107974086-A A kind of transparent type resin combination for electric wire tubing and preparation method thereof 惠州市永耐宝新材料有限公司 2018-05-01 CN claimed
CN-105602324-A Antibacterial watercolor and preparation method thereof FOSHAN JUCHENG BIOCHEMICAL TECH RES AND DEV CO LTD 2016-05-25 CN claimed
CN-107974086-A A kind of transparent type resin combination for electric wire tubing and preparation method thereof 惠州市永耐宝新材料有限公司 2018-05-01 CN disclosed
CN-107974086-A A kind of transparent type resin combination for electric wire tubing and preparation method thereof 惠州市永耐宝新材料有限公司 2018-05-01 CN disclosed
CN-106348376-A Method of separating pollutants from waste water and system thereof 诚信工业有限公司 2017-01-25 CN disclosed
CN-105602324-A Antibacterial watercolor and preparation method thereof FOSHAN JUCHENG BIOCHEMICAL TECH RES AND DEV CO LTD 2016-05-25 CN disclosed