SCHEMBL2806200

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30963914	1.00	CYP2A6 (0.50)	CYP2A6GRM5ERN1CYP2C9CYP2B6
	SCHEMBL29793188	0.85	CYP2A6 (0.50)	CYP2A6GRM5ERN1CYP2C9CYP2B6
	SCHEMBL3796332	0.82	CYP2A6 (0.67)	CYP2A6GRM5CYP2C9CYP2B6CYP2C19
	SCHEMBL718295	0.82	CA12 (0.60)	GRM5CYP2C9CYP3A4CA12CA1
	SCHEMBL27952686	0.81	CA12 (0.53)	GRM5CYP3A4CA12CA1CA2
	SCHEMBL1477031	0.78	GRM5 (0.50)	CYP2A6GRM5CYP2C9CYP2B6CYP2C19
	SCHEMBL30669242	0.78	GRM5 (0.50)	CYP2A6GRM5CYP2C9CYP2B6CYP2C19
	SCHEMBL1477185	0.78	GRM5 (0.50)	CYP2A6GRM5CYP2C9CYP2B6CYP2C19
	SCHEMBL2806708	0.78	MEN1 (0.55)	CYP2A6GRM5CYP2C9CYP2B6CYP2C19
	SCHEMBL31673182	0.78	GRM5 (0.71)	CYP2A6GRM5CYP2C9CYP2B6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.