Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.65 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.65 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.63 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.61 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.61 |
| ▸ | GRM5 | P41594 | 5/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13907278 | 0.95 | CYP2A6 (0.62) | CYP2A6CYP2C9CYP2B6CYP2C19CYP2D6 | |
| SCHEMBL31673222 | 0.93 | GRM5 (0.64) | CYP2A6CYP2C9CYP2B6CYP2C19CYP2D6 | |
| SCHEMBL401836 | 0.93 | GRM5 (0.64) | CYP2A6CYP2C9CYP2B6CYP2C19CYP2D6 | |
| SCHEMBL31673242 | 0.91 | CYP2A6 (0.58) | CYP2A6CYP2C9CYP2B6CYP2C19CYP2D6 | |
| SCHEMBL5368902 | 0.85 | — | — | |
| SCHEMBL21252739 | 0.85 | — | — | |
| SCHEMBL15302246 | 0.85 | — | — | |
| SCHEMBL4038063 | 0.85 | — | — | |
| SCHEMBL7834182 | 0.85 | — | — | |
| SCHEMBL4033948 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250257076-A1 | SUBSTITUTED PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AS cGAS INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2025-08-14 | — | — | US | disclosed |
| US-20150273457-A1 | HIGHLY ACTIVE MULTIDENTATE CATALYSTS FOR EFFICIENT ALKYNE METATHESIS | NATIONAL SCIENCE FOUNDATION | 2015-10-01 | — | — | US | disclosed |
| US-20150273457-A1 | HIGHLY ACTIVE MULTIDENTATE CATALYSTS FOR EFFICIENT ALKYNE METATHESIS | NATIONAL SCIENCE FOUNDATION | 2015-10-01 | — | — | US | disclosed |
| US-8993804-B2 | Highly active multidentate catalysts for efficient alkyne metathesis | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2015-03-31 | — | — | US | disclosed |
| US-8993470-B2 | Catalysts for the alkyne metathesis | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-8993804-B2 | Highly active multidentate catalysts for efficient alkyne metathesis | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2015-03-31 | — | — | US | disclosed |
| US-8993470-B2 | Catalysts for the alkyne metathesis | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2015-03-31 | — | — | US | disclosed |
| EP-2638022-B1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL MYERS SQUIBB CO (US) | 2014-12-24 | — | — | EP | disclosed |
| EP-2556078-B1 | CATALYSTS FOR ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2014-09-24 | — | — | EP | disclosed |
| US-20130261295-A1 | Highly Active Multidentate Catalysts for Efficient Alkyne Metathesis | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2013-10-03 | — | — | US | disclosed |
| US-20130144102-A1 | CATALYSTS FOR THE ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2013-06-06 | — | — | US | disclosed |
| US-20130144102-A1 | CATALYSTS FOR THE ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2013-06-06 | — | — | US | disclosed |
| US-20100222432-A1 | Synthetic Carbon Nanotubes | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION | 2010-09-02 | — | — | US | disclosed |
| US-20100222432-A1 | Synthetic Carbon Nanotubes | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION | 2010-09-02 | — | — | US | disclosed |
| US-20100222432-A1 | Synthetic Carbon Nanotubes | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION | 2010-09-02 | — | — | US | disclosed |
| US-20090082574-A1 | Metallacycles and methods of making the same | ACADEMIA SINICA (TW) | 2009-03-26 | — | — | US | disclosed |
| WO-2008048227-A2 | SYNTHETIC CARBON NANOTUBES | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2008-04-24 | — | — | WO | disclosed |
| WO-2008048227-A2 | SYNTHETIC CARBON NANOTUBES | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2008-04-24 | — | — | WO | disclosed |
| US-7186380-B2 | Transistor and sensors made from molecular materials with electric dipoles | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186380-B2 | Transistor and sensors made from molecular materials with electric dipoles | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2007-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222432-A1 | Synthetic Carbon Nanotubes | CYCS, CHN2, TUBA3C | CYP2A6 3737/4885CYP2C9 2069/4885CYP2B6 3474/4885 |
| US-20150273457-A1 | HIGHLY ACTIVE MULTIDENTATE CATALYSTS FOR EFFICIENT ALKYNE METATHESIS | PCNA, TRIM58, CAD | CYP2A6 2625/4885CYP2C9 3445/4885CYP2B6 2471/4885 |
| US-20090082574-A1 | Metallacycles and methods of making the same | SOD1, PMS2, MEN1 | CYP2A6 380/4885CYP2C9 1245/4885CYP2B6 852/4885 |
| US-20130144102-A1 | CATALYSTS FOR THE ALKYNE METATHESIS | MSH6, AP3M1, PMS2 | CYP2A6 796/4885CYP2C9 1880/4885CYP2B6 444/4885 |
| US-20130261295-A1 | Highly Active Multidentate Catalysts for Efficient Alkyne Metathesis | PCNA, TRIM58, CAD | CYP2A6 2625/4885CYP2C9 3445/4885CYP2B6 2471/4885 |
| US-20250257076-A1 | SUBSTITUTED PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AS cGAS INHIBITORS | CGAS, SSB, FPGS | CYP2A6 3603/4885CYP2C9 1642/4885CYP2B6 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.