SCHEMBL28062031

SCHEMBL28062031

Cc1ccccc1C(CC(=O)O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.51
MEN1 O00255 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
KMT2A Q03164 1/20 0.51
GABBR2 O75899 1/20 0.50
GABBR1 Q9UBS5 1/20 0.50
ACP3 P15309 1/20 0.50
LMNA P02545 1/20 0.49
TAAR1 Q96RJ0 1/20 0.49
CTSA P10619 6/20 0.46
MAPT P10636 1/20 0.45
GAA P10253 2/20 0.45
NR3C2 P08235 1/20 0.45
FFAR1 O14842 1/20 0.44
TSHR P16473 1/20 0.43
GPBAR1 Q8TDU6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2794839 0.90 CTSA (0.49) GABBR2GABBR1ACP3CTSA
SCHEMBL1390346 0.89 GPBAR1 (0.56) HPGDMEN1CYP1A2CYP3A4CYP2C9
SCHEMBL14509741 0.87 CYP2C9 (0.50) HPGDMEN1CYP1A2CYP3A4CYP2C9
SCHEMBL30781885 0.85 GABBR2 (0.48) GABBR2GABBR1ACP3CTSA
SCHEMBL658439 0.85 GABBR2 (0.48) GABBR2GABBR1ACP3CTSA
SCHEMBL364753 0.85 CTSA (0.56) HPGDMEN1CYP1A2CYP3A4CYP2C9
SCHEMBL14081313 0.80 CTSA (0.45) GABBR2GABBR1CTSA
3,3-Diphenylpropanoic Acid SCHEMBL66473 0.80 GABBR2 (0.59) HPGDCYP2C19GABBR2GABBR1LMNA
3,3-Diphenylpropanoic Acid SCHEMBL5283373 0.80 GABBR2 (0.59) HPGDCYP2C19GABBR2GABBR1LMNA
SCHEMBL2320843 0.79 CTSA (0.47) GABBR2GABBR1ACP3CTSA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115197036-B Method for performing anti-mahalanobis hydrogen carboxylation reaction on photocatalytic olefin compound and carbon dioxide 中国科学院理化技术研究所 2024-01-23 CN disclosed
CN-115197036-A Method for carrying out anti-Ma hydrocarboxylation reaction on olefin compound and carbon dioxide by photocatalysis 中国科学院理化技术研究所 2022-10-18 CN disclosed
CN-105431510-A Organic compounds GIVAUDAN SA 2016-03-23 CN disclosed