SCHEMBL28062102

SCHEMBL28062102

O=C1CCCN1C1CC(c2ccccc2Cl)=NO1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.52
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
HPGD P15428 4/20 0.44
MAPT P10636 4/20 0.44
ALDH1A1 P00352 4/20 0.44
NPC1 O15118 4/20 0.44
RAB9A P51151 4/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 2/20 0.42
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GAA P10253 1/20 0.39
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
PLA2G1B P04054 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28062125 0.80 CHRM1 (0.54) CHRM1CA1CA2HPGDMAPT
SCHEMBL31103576 0.74 CHRM1 (0.54) CHRM1
SCHEMBL6783767 0.74 CHRM1 (0.51) CHRM1MAPTALDH1A1SMN1; SMN2MEN1
SCHEMBL28828294 0.72 CHRM1 (0.54) CHRM1ALDH1A1NPC1RAB9ALMNA
SCHEMBL13170185 0.69 CHRM1 (0.53) CHRM1L3MBTL1
SCHEMBL6779518 0.68 CHRM1 (1.00) CHRM1
SCHEMBL10388432 0.66 CA1 (0.72) CA1CA2HPGDMAPTALDH1A1
SCHEMBL12294344 0.64 MAPT (0.54) CA1CA2HPGDMAPTALDH1A1
SCHEMBL21066142 0.64 CA1 (0.51) CA1CA2HPGDMAPTALDH1A1
SCHEMBL6777537 0.64 CHRM1 (0.45) CHRM1KMT2ACYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105435760-A Click preparation and application of allyl cationic cyclodextrin chiral resolution material UNIV TIANJIN 2016-03-30 CN disclosed