Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.51 |
| ▸ | MAT2A | P31153 | 9/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28062455 | 0.94 | ENPP2 (0.51) | ENPP2MAT2APRMT5CYP3A4AKR1B1 | |
| SCHEMBL28062456 | 0.91 | ENPP2 (0.53) | ENPP2MAT2APRMT5CYP3A4AKR1B1 | |
| SCHEMBL670444 | 0.87 | ENPP2 (0.54) | ENPP2MAT2APRMT5CYP3A4AKR1B1 | |
| SCHEMBL671374 | 0.83 | ENPP2 (0.59) | ENPP2MAT2APRMT5CYP3A4AKR1B1 | |
| SCHEMBL671281 | 0.80 | ENPP2 (0.53) | ENPP2MAT2APRMT5CYP3A4AKR1B1 | |
| SCHEMBL671724 | 0.79 | ENPP2 (0.52) | ENPP2MAT2APRMT5CYP3A4AKR1B1 | |
| SCHEMBL670399 | 0.79 | ENPP2 (0.80) | ENPP2MAT2APRMT5CYP3A4AKR1B1 | |
| SCHEMBL671004 | 0.79 | ENPP2 (0.65) | ENPP2MAT2APRMT5CYP3A4CYP1A2 | |
| SCHEMBL671544 | 0.78 | ENPP2 (0.51) | ENPP2CYP3A4AKR1B1PTGDR2CYP1A2 | |
| SCHEMBL670405 | 0.78 | ENPP2 (0.56) | ENPP2MAT2APRMT5CYP3A4AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103201262-B | Autotaxin inhibitors and application thereof | AMIRA PHARMACEUTICALS, INC. (US) | 2016-06-01 | — | — | CN | disclosed |