SCHEMBL28062696

SCHEMBL28062696

CCCCCCCCCCCCCCCCCCc1cc2ccccc2nc1-c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 6/20 0.62
PDE10A Q9Y233 1/20 0.51
GPR84 Q9NQS5 1/20 0.49
MEN1 O00255 2/20 0.45
CYP1A2 P05177 2/20 0.45
KMT2A Q03164 2/20 0.45
CYP2C9 P11712 1/20 0.45
CRHBP P24387 1/20 0.45
CYP2C19 P33261 1/20 0.45
CRHR2 Q13324 1/20 0.45
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GLA P06280 1/20 0.44
CYP3A4 P08684 1/20 0.44
GAA P10253 1/20 0.44
HPGD P15428 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27640114 1.00 TLR8 (0.62) TLR8PDE10AGPR84MEN1CYP1A2
SCHEMBL16198056 1.00 TLR8 (0.62) TLR8PDE10AGPR84MEN1CYP1A2
SCHEMBL27640113 1.00 TLR8 (0.62) TLR8PDE10AGPR84MEN1CYP1A2
SCHEMBL27640115 1.00 TLR8 (0.62) TLR8PDE10AGPR84MEN1CYP1A2
SCHEMBL27660900 0.98 TLR8 (0.64) TLR8PDE10AGPR84MEN1CYP1A2
SCHEMBL27660917 0.94 TLR8 (0.63) TLR8PDE10AGPR84MEN1CYP1A2
SCHEMBL28214645 0.88 PDE10A (0.57) TLR8PDE10AKMT2AMAPTKDM4E
SCHEMBL27900923 0.81 TLR8 (0.61) TLR8
SCHEMBL20081370 0.81 PDE10A (0.61) TLR8PDE10AMEN1KMT2AMAPT
SCHEMBL18597464 0.80 TLR8 (0.44) TLR8PDE10AGPR84MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109554122-A Polarizing coating curing type adhesive, polarizing coating, optical film and image display device 日东电工株式会社 2019-04-02 CN disclosed
CN-109536046-A Polarizing coating curing type adhesive, polarizing coating, optical film and image display device 日东电工株式会社 2019-03-29 CN disclosed
CN-105492564-B Curing adhesive for polarizing film, optical film, and image display device 日东电工株式会社 2018-12-11 CN disclosed
CN-105102561-B Active energy ray curable adhesive compound, polarizing coating and its manufacture method, optical film and image display device 日东电工株式会社 2018-05-11 CN disclosed
CN-104185803-B Polarized film, optical film, and image display device 日东电工株式会社 2017-05-24 CN disclosed
CN-104395420-B Active energy ray curable adhesive composition, polarizing film and method for producing same, optical film and image display device 日东电工株式会社 2017-05-24 CN disclosed
CN-104395419-B Active energy ray curable adhesive compound, polarizing coating and its manufacture method, blooming and image display device 日东电工株式会社 2017-03-08 CN disclosed
CN-105849598-A Laminated polarizing film, manufacturing method therefor, laminated optical film, and image display device 日东电工株式会社 2016-08-10 CN disclosed