SCHEMBL28062855

SCHEMBL28062855

CCCO[Si](CC)(OCCC)c1cccc(Br)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 3/20 0.39
GAA P10253 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
HPGD P15428 2/20 0.34
FBP1 P09467 1/20 0.34
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
ERBB2 P04626 1/20 0.33
ERBB4 Q15303 1/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C19 P33261 2/20 0.33
IDO1 P14902 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28062925 0.90 EGFR (0.41) EGFRGAAALDH1A1MAPK1L3MBTL1
SCHEMBL17937733 0.86 ALDH1A1 (0.39) EGFRGAAALDH1A1MAPK1L3MBTL1
SCHEMBL28062856 0.86 EGFR (0.38) EGFRGAAALDH1A1MAPK1L3MBTL1
SCHEMBL28062737 0.83 EGFR (0.39) EGFRGAAALDH1A1MAPK1L3MBTL1
SCHEMBL17937640 0.83 EGFR (0.40) EGFRGAAALDH1A1MAPK1L3MBTL1
SCHEMBL28062847 0.81 EGFR (0.39) EGFRGAAALDH1A1MAPK1L3MBTL1
SCHEMBL28062705 0.81 ALDH1A1 (0.38) EGFRGAAALDH1A1MAPK1L3MBTL1
SCHEMBL28062704 0.80 KMT2A (0.38) ALDH1A1L3MBTL1CYP1A2CYP2C19IDO1
SCHEMBL28062801 0.80 EGFR (0.41) EGFRGAAALDH1A1MAPK1L3MBTL1
SCHEMBL28062699 0.79 MAPT (0.33) ALDH1A1HPGDLMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105555901-A Polishing composition FUJIMI INC 2016-05-04 CN disclosed