Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | FDPS | P14324 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27901401 | 0.97 | LMNA (0.54) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL28357779 | 0.97 | LMNA (0.54) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL17766889 | 0.97 | LMNA (0.54) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL28357777 | 0.97 | LMNA (0.54) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL18107230 | 0.97 | LMNA (0.54) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL28605961 | 0.97 | LMNA (0.54) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL28539807 | 0.97 | LMNA (0.54) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL18107409 | 0.97 | LMNA (0.54) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL16737284 | 0.97 | LMNA (0.54) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL28024712 | 0.97 | LMNA (0.54) | LMNADNM1ALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106380431-A | Synthetic method for 1,4-dithioalkyl benzene and halide thereof | 湘潭大学 | 2017-02-08 | — | — | CN | disclosed |
| CN-105555757-A | Compositions and methods for delivering messenger RNA | PROTIVA BIOTHERAPEUTICS INC | 2016-05-04 | — | — | CN | disclosed |