Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 1.00 |
| ▸ | PPARA | Q07869 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2806311 | 1.00 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL4158584 | 1.00 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL2805642 | 0.91 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL2805640 | 0.91 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL7711541 | 0.90 | PPARG (0.80) | PPARGPPARA | |
| SCHEMBL7711546 | 0.90 | PPARG (0.80) | PPARGPPARA | |
| SCHEMBL28303067 | 0.83 | PPARG (0.76) | PPARGPPARA | |
| SCHEMBL6182299 | 0.82 | GPR132 (0.77) | PPARG | |
| SCHEMBL27871431 | 0.82 | GPR132 (0.77) | PPARG | |
| SCHEMBL6605281 | 0.82 | PPARG (0.86) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137794-A1 | Retinoic acid receptor (RAR) agonists, agonists for steroid/thyroid hormone receptor superfamily, and an agonist for a heterodimer partner | SALK INSTITUTE FOR BIOLOGICAL STUDIES, THE | 2002-09-26 | — | — | US | claimed |
| US-6436993-B1 | SYNERGISTIC MIXTURES OF RETINOIC ACID RECEPTOR (RAR) ANTAGONISTS AND STEROID, THYROID OR RETINOID RECEPTOR AGONISTS SUCH AS PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS USED TO CONTROL CELLULAR PROCESSES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2002-08-20 | — | — | US | claimed |
| WO-2001003659-A1 | USE OF RAR ANTAGONISTS AS MODULATORS OF HORMONE MEDIATED PROCESSES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2001-01-18 | — | — | WO | claimed |
| US-20110300129-A1 | SYSTEMS AND METHODS FOR ENHANCING VACCINE EFFICACY | UNIVERSITY OF ROCHESTER (US) | 2011-12-08 | — | — | US | disclosed |
| WO-2010075037-A1 | SYSTEMS AND METHODS FOR ENHANCING VACCINE EFFICACY | UNIVERSITY OF ROCHESTER (US) | 2010-07-01 | — | — | WO | disclosed |
| EP-2081599-A2 | COMPOUNDS, KITS AND METHODS FOR CONFERRING CYTOPROTECTION | University of Debrecen (HU) | 2009-07-29 | — | — | EP | disclosed |
| US-20090155228-A1 | COMPOUNDS, KITS AND METHODS FOR CONFERRING CYTOPROTECTION | UNIVERSITY OF DEBRECEN (HU) | 2009-06-18 | — | — | US | disclosed |
| WO-2007144679-A2 | COMPOUNDS, KITS AND METHODS FOR CONFERRING CYTOPROTECTION | UNIVERSITY OF DEBRECEN (HU) | 2007-12-21 | — | — | WO | disclosed |
| US-20020137794-A1 | Retinoic acid receptor (RAR) agonists, agonists for steroid/thyroid hormone receptor superfamily, and an agonist for a heterodimer partner | SALK INSTITUTE FOR BIOLOGICAL STUDIES, THE | 2002-09-26 | — | — | US | disclosed |
| US-6436993-B1 | SYNERGISTIC MIXTURES OF RETINOIC ACID RECEPTOR (RAR) ANTAGONISTS AND STEROID, THYROID OR RETINOID RECEPTOR AGONISTS SUCH AS PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS USED TO CONTROL CELLULAR PROCESSES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2002-08-20 | — | — | US | disclosed |
| WO-2001003659-A1 | USE OF RAR ANTAGONISTS AS MODULATORS OF HORMONE MEDIATED PROCESSES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2001-01-18 | — | — | WO | disclosed |