SCHEMBL28063808

SCHEMBL28063808

C=CC(=O)OCCC[SiH2]OCC.CCO[SiH](OCC)OCC

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.50
HPGD P15428 1/20 0.50
ALDH1A1 P00352 3/20 0.46
CYP3A4 P08684 1/20 0.46
TP53 P04637 2/20 0.39
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 1/20 0.39
THRB P10828 2/20 0.37
ATM Q13315 1/20 0.34
HCAR2 Q8TDS4 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL28849367 0.97 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28205970 0.96 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28206341 0.96 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28254775 0.93 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28135053 0.92 TSHR (0.51) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28072244 0.91 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL1015223 0.91 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28029882 0.90 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
Phosphine SCHEMBL28175773 0.90 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28267119 0.89 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110437655-A TiO2Modified polyacrylate/organic-silicon hybridization coating and preparation method thereof HUAIYIN INST TECHNOLOGY 2019-11-12 CN claimed
CN-110407975-A Preparation method of silicon dioxide and titanium dioxide hybrid hydrogel UNIV SICHUAN SCI & ENG 2019-11-05 CN claimed
CN-109666102-B A kind of the ASA graft copolymer and preparation method of chemical modification efficient heat-resisting 四川中物材料股份有限公司 2019-11-05 CN claimed
CN-110396387-A A kind of hot activation is without just viscous sealant and its preparation method and application NINGBO KAFEIMU NEW MAT CO LTD 2019-11-01 CN claimed
CN-106753217-B A kind of preparation method of novel heat cure liquid silastic 山东大学 2019-06-28 CN claimed
CN-106947031-B A kind of flucride siloxane fire retardant and the preparation method and application thereof 铨盛聚碳科技股份有限公司 2019-06-04 CN claimed
CN-109666102-A A kind of the ASA graft copolymer and preparation method of chemical modification efficient heat-resisting 四川中物材料股份有限公司 2019-04-23 CN claimed
CN-106595908-B A kind of pressure sensor 张红卫 2019-04-05 CN claimed
CN-107304051-B A kind of inorganic nano Porous materials and preparation method thereof 中国科学院化学研究所 2019-03-26 CN claimed
CN-109251284-A One kind can ambient cross-linking polyacrylate elastomer and preparation method thereof 常州大学 2019-01-22 CN claimed
CN-107541180-A A kind of acid room temperature sealing silicone sulfide glue 山东三泽硅胶有限公司 2018-01-05 CN claimed
CN-107352549-A A kind of preparation method of hollow glass micropearl 张振 2017-11-17 CN claimed
CN-105623626-B The compositions of additives of drilling fluid is with high temperature resistance without native mutually full oil base drilling fluid 中国石油大学(北京) 2017-10-31 CN claimed
CN-107304051-A A kind of inorganic nano Porous materials and preparation method thereof 中国科学院化学研究所 2017-10-31 CN claimed
CN-104704058-B Device used for image display obstruction material composition and use its image display device 迈图高新材料日本合同公司 2017-09-22 CN claimed
CN-104631208-B Release coating and release liners and the application in multicomponent reactive polyurethane leather is manufactured 浙江池河科技有限公司 2017-07-07 CN claimed
CN-104031289-B Polyolefin composite diaphragm and preparation method thereof, and lithium ion battery 江苏华东锂电技术研究院有限公司 2017-06-13 CN claimed
CN-106753217-A A kind of preparation method of Novel hot vulcanized liquid silicon rubber 山东大学 2017-05-31 CN claimed
CN-106595908-A Pressure sensor 张红卫 2017-04-26 CN claimed
CN-104124416-B Polyolefin composite diaphragm and preparation method thereof, and lithium ion battery JIANGSU HUADONG INSTITUTE OF LI-ION BATTERY CO., LTD. (CN) 2016-11-30 CN claimed