SCHEMBL28064157

SCHEMBL28064157

C=Cc1ccc(O)cc1OC(=O)CCCCCCC/C=C\C/C=C\CCCCC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.49
POLM Q9NP87 1/20 0.48
POLK Q9UBT6 1/20 0.48
POLL Q9UGP5 1/20 0.48
POLH Q9Y253 1/20 0.48
CNR1 P21554 2/20 0.47
ALDH1A1 P00352 5/20 0.46
HPGD P15428 2/20 0.46
GLA P06280 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46
CNR2 P34972 1/20 0.46
HTR2A P28223 1/20 0.46
PSMB11 A5LHX3 1/20 0.46
PSMA7 O14818 1/20 0.46
PSMB1 P20618 1/20 0.46
PSMA1 P25786 1/20 0.46
PSMA2 P25787 1/20 0.46
PSMA3 P25788 1/20 0.46
PSMA4 P25789 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27912643 0.85 ELANE (0.52) ELANEPOLMPOLKPOLLPOLH
SCHEMBL11044984 0.82 POLM (0.58) ELANEPOLMPOLKPOLLPOLH
SCHEMBL3948637 0.81 CNR2 (0.60) ELANEPOLMPOLKPOLLPOLH
SCHEMBL562484 0.81 ELANE (0.48) ELANEPOLMPOLKPOLLPOLH
SCHEMBL562485 0.81 ELANE (0.48) ELANEPOLMPOLKPOLLPOLH
SCHEMBL17078363 0.78 PSMB11 (0.56) CNR1ALDH1A1HPGDMAPTCNR2
SCHEMBL562207 0.78 ELANE (0.46) ELANEPOLMPOLKPOLLPOLH
SCHEMBL562208 0.78 ELANE (0.46) ELANEPOLMPOLKPOLLPOLH
SCHEMBL27579253 0.76 KDM4E (0.54) POLMPOLKPOLLPOLHTHRB
SCHEMBL10940165 0.76 PSMB11 (0.59) ELANEPOLMPOLKPOLLPOLH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103228320-B Carbonate derivatives as skin care EASTMAN CHEMICAL CO. (US) 2016-04-20 CN disclosed