Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.60 |
| ▸ | CNR1 | P21554 | 9/20 | 0.60 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.51 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.51 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.51 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.51 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.48 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.48 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.48 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.48 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.48 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.48 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.48 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946747 | 0.93 | CNR2 (0.67) | CNR2CNR1MEN1TP53CYP3A4 | |
| SCHEMBL27912643 | 0.91 | ELANE (0.52) | CNR2CNR1ELANEPOLMPOLK | |
| SCHEMBL3950873 | 0.84 | CNR2 (0.57) | CNR2CNR1MEN1TP53CYP3A4 | |
| SCHEMBL10780257 | 0.84 | THRA (0.61) | ELANEPOLMPOLKPOLLPOLH | |
| SCHEMBL3952691 | 0.83 | CNR2 (0.57) | CNR2CNR1MEN1TP53CYP3A4 | |
| SCHEMBL3034727 | 0.83 | CNR2 (0.57) | CNR2CNR1MEN1TP53CYP3A4 | |
| SCHEMBL28064157 | 0.81 | ELANE (0.49) | CNR2CNR1ELANEPOLMPOLK | |
| SCHEMBL27293376 | 0.80 | CNR2 (0.55) | CNR2CNR1MEN1TP53CYP3A4 | |
| SCHEMBL3030328 | 0.79 | CNR2 (0.55) | CNR2CNR1MEN1TP53CYP3A4 | |
| SCHEMBL562484 | 0.79 | ELANE (0.48) | CNR1ELANEPOLMPOLKPOLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021590-A1 | TYROSINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2009-02-19 | — | — | WO | claimed |
| WO-2009021590-A1 | TYROSINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |