Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31225162 | 0.91 | MAPT (0.73) | MAPTNPSR1HSPB1RAB9AGAA | |
| SCHEMBL15055186 | 0.91 | MAPT (0.73) | MAPTNPSR1HSPB1RAB9AGAA | |
| SCHEMBL15055631 | 0.87 | MAPT (0.67) | MAPTNPSR1HSPB1RAB9AGAA | |
| SCHEMBL20932230 | 0.86 | HSPB1 (0.82) | MAPTNPSR1HSPB1RAB9AGAA | |
| SCHEMBL10465836 | 0.86 | HSPB1 (0.68) | MAPTNPSR1HSPB1RAB9AGAA | |
| SCHEMBL15055593 | 0.85 | MAPT (0.65) | MAPTNPSR1HSPB1RAB9AGAA | |
| SCHEMBL15055652 | 0.84 | MAPT (0.64) | MAPTNPSR1HSPB1RAB9AGAA | |
| SCHEMBL177664 | 0.84 | HSPB1 (0.73) | MAPTNPSR1HSPB1RAB9AGAA | |
| SCHEMBL10468493 | 0.84 | HSPB1 (0.73) | MAPTNPSR1HSPB1RAB9AGAA | |
| SCHEMBL28033541 | 0.82 | HSPB1 (0.71) | MAPTNPSR1HSPB1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541703-A | Triamine monomer containing pyridine structure and preparation method thereof | UNIV JILIN | 2016-05-04 | — | — | CN | disclosed |