Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Sulfosalicylic. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfosalicylic SCHEMBL27615566 | 0.85 | ALDH1A1 (0.86) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| Sulfosalicylic SCHEMBL5370629 | 0.85 | KDM4E (0.49) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| Sulfosalicylic SCHEMBL29417853 | 0.85 | KDM4E (0.49) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL27373563 | 0.84 | POLB (0.50) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| Sulfosalicylic SCHEMBL8769458 | 0.83 | KDM4E (0.51) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| Sulfosalicylic SCHEMBL28868326 | 0.83 | ALDH1A1 (0.89) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| Sulfosalicylic SCHEMBL29364125 | 0.82 | ALDH1A1 (0.96) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL3527141 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| Sulfosalicylic SCHEMBL34766 | 0.82 | ALDH1A1 (0.96) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| Sulfosalicylic SCHEMBL6717073 | 0.82 | ALDH1A1 (0.96) | ALDH1A1KDM4EHSD17B10HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108889144-B | Protein pollution resistant fiber membrane and preparation method and application thereof | 贵阳学院 | 2020-07-10 | — | — | CN | claimed |
| CN-108889144-B | Protein pollution resistant fiber membrane and preparation method and application thereof | 贵阳学院 | 2020-07-10 | — | — | CN | disclosed |
| CN-105665434-A | Soil disinfection and soil remediation combined technology | 潍坊市新友吉土壤消毒服务专业合作社 | 2016-06-15 | — | — | CN | disclosed |