Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28899983 | 0.84 | HTT (0.49) | NR4A2HTTACHEBCHEMPO | |
| SCHEMBL1748521 | 0.79 | POLB (0.50) | POLBNR4A2ACHEBCHECHRM1 | |
| SCHEMBL29909644 | 0.79 | POLB (0.50) | POLBNR4A2ACHEBCHECHRM1 | |
| SCHEMBL3314521 | 0.76 | NR4A2 (0.53) | POLBNR4A2HTTACHEBCHE | |
| SCHEMBL28220511 | 0.76 | POLB (0.47) | POLBNR4A2ACHEBCHECHRM1 | |
| SCHEMBL28010173 | 0.75 | MAOA (0.52) | HTTACHECHRM1KMT2AALDH1A1 | |
| SCHEMBL28129920 | 0.72 | POLB (0.47) | POLBNR4A2ACHEBCHECHRM1 | |
| SCHEMBL31252837 | 0.72 | POLB (0.47) | POLBNR4A2ACHEBCHECHRM1 | |
| SCHEMBL2170302 | 0.72 | POLB (0.47) | POLBNR4A2ACHEBCHECHRM1 | |
| SCHEMBL3973470 | 0.72 | POLB (0.44) | POLBNR4A2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028491-A | Fibroblast growth factor receptor inhibitor | 蓝图药品公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-105658642-A | Fibroblast growth factor receptor inhibitors | 蓝图药品公司 | 2016-06-08 | — | — | CN | disclosed |