SCHEMBL28064520

SCHEMBL28064520

CC(O)=COc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 9/20 0.62
ALDH1A1 P00352 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
SRD5A2 P31213 2/20 0.49
STS P08842 1/20 0.49
GAA P10253 1/20 0.49
NPC1 O15118 1/20 0.46
HPGD P15428 1/20 0.46
RAB9A P51151 1/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9602185 0.80 CA4 (0.42) ELANEALDH1A1L3MBTL1SMN1; SMN2HPGD
SCHEMBL6306408 0.80 CA4 (0.42) ELANEALDH1A1L3MBTL1SMN1; SMN2HPGD
SCHEMBL9602190 0.80 CA4 (0.42) ELANEALDH1A1L3MBTL1SMN1; SMN2HPGD
SCHEMBL3438590 0.79 ELANE (0.58) ELANEALDH1A1L3MBTL1SRD5A2STS
SCHEMBL28649673 0.79 ELANE (0.58) ELANEALDH1A1L3MBTL1HTTSMN1; SMN2
SCHEMBL39352 0.78 ELANE (0.56) ELANEALDH1A1L3MBTL1SRD5A2STS
SCHEMBL1590016 0.77 ELANE (1.00) ELANEALDH1A1HTTGAANPC1
Ethylene SCHEMBL27799966 0.76 ELANE (0.55) ELANEALDH1A1L3MBTL1SRD5A2STS
SCHEMBL28145862 0.76 ELANE (0.55) ELANEALDH1A1L3MBTL1SRD5A2STS
SCHEMBL6618691 0.75 CES2 (0.77) ELANEALDH1A1L3MBTL1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113746035-B Method for improving interface voltage resistance of prefabricated cable accessory rubber stress control body 哈尔滨理工大学 2022-12-09 CN claimed
CN-105461845-A Method for synthesizing ultraviolet-resistance compound emulsion CHONGQING LEHU TECHNOLOGY CO LTD 2016-04-06 CN disclosed