Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11007169 | 0.75 | SLC6A2 (0.37) | SLC6A2SLC6A3SLC6A4CHRM2CHRM4 | |
| SCHEMBL11007172 | 0.74 | HSD17B10 (0.41) | SLC6A2SLC6A3SLC6A4CHRM2CHRM4 | |
| SCHEMBL11036308 | 0.71 | CHRM2 (0.38) | SLC6A2SLC6A3SLC6A4CHRM2CHRM4 | |
| SCHEMBL18115398 | 0.70 | CHRM2 (0.44) | SLC6A2SLC6A3SLC6A4CHRM2CHRM4 | |
| SCHEMBL14777960 | 0.70 | GRIN1 (0.44) | CHRM2CHRM4CHRM1CHRM3CYP1A2 | |
| SCHEMBL10368267 | 0.69 | SLC6A2 (0.45) | SLC6A2SLC6A3SLC6A4CHRM2CHRM4 | |
| SCHEMBL11004480 | 0.69 | SLC6A2 (0.36) | SLC6A2SLC6A3SLC6A4CHRM2CHRM4 | |
| SCHEMBL11004483 | 0.68 | HSD17B10 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL11006233 | 0.68 | CYP19A1 (0.54) | KDM4ELMNA | |
| SCHEMBL11006245 | 0.68 | ADRA2A (0.45) | SLC6A2SLC6A3SLC6A4CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658628-A | Novel arylalkene derivatives and use thereof as selective estrogen receptor modulators | 北京赛林泰医药技术有限公司 | 2016-06-08 | — | — | CN | disclosed |