Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.63 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.49 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19091685 | 0.82 | SIGMAR1 (0.47) | SIGMAR1P2RX4ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL16563486 | 0.80 | HDAC3 (0.52) | SIGMAR1P2RX4ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL29531062 | 0.80 | HDAC3 (0.52) | SIGMAR1P2RX4ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL18500034 | 0.78 | SIGMAR1 (0.44) | SIGMAR1P2RX4ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL30216960 | 0.76 | SIGMAR1 (0.46) | SIGMAR1P2RX4SMPD1P2RX1P2RX3 | |
| SCHEMBL32685462 | 0.76 | SIGMAR1 (0.46) | SIGMAR1P2RX4SMPD1P2RX1P2RX3 | |
| SCHEMBL24631312 | 0.76 | SIGMAR1 (0.46) | SIGMAR1P2RX4SMPD1MEN1KMT2A | |
| SCHEMBL14464161 | 0.76 | SIGMAR1 (0.46) | SIGMAR1P2RX4SMPD1P2RX1P2RX3 | |
| SCHEMBL29759083 | 0.76 | SIGMAR1 (0.50) | SIGMAR1P2RX4ALDH1A1SMPD1P2RX1 | |
| SCHEMBL7696530 | 0.76 | SIGMAR1 (0.50) | SIGMAR1P2RX4ALDH1A1SMPD1P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579549-A | ELECTROCHROMIC COMPOSITION | ESSILOR INT | 2016-05-11 | — | — | CN | claimed |
| CN-105555912-A | Electrochromic composition | ESSILOR INT CIE GENERALE D OPTIQUE | 2016-05-04 | — | — | CN | claimed |
| CN-105579549-A | ELECTROCHROMIC COMPOSITION | ESSILOR INT | 2016-05-11 | — | — | CN | disclosed |
| CN-105555912-A | Electrochromic composition | ESSILOR INT CIE GENERALE D OPTIQUE | 2016-05-04 | — | — | CN | disclosed |