Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27626763 | 0.86 | PRCP (0.44) | PRCPTDP1SMN1; SMN2KMT2AMEN1 | |
| Tert-Butyl Formate SCHEMBL28209963 | 0.85 | PRCP (0.35) | PRCPTDP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2707254 | 0.84 | PRCP (0.47) | PRCPSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL29330477 | 0.84 | PRCP (0.47) | PRCPSMN1; SMN2KMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL29116034 | 0.82 | PRCP (0.46) | PRCPSMN1; SMN2KMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL29116032 | 0.82 | PRCP (0.46) | PRCPSMN1; SMN2KMT2AMEN1LMNA | |
| Tert-Butyl Formate SCHEMBL28828186 | 0.82 | MEN1 (0.42) | SMN1; SMN2KMT2AMEN1MAPTGAA | |
| Tert-Butyl Formate SCHEMBL28065019 | 0.80 | PRCP (0.31) | PRCPTDP1 | |
| Tert-Butyl Formate SCHEMBL27651272 | 0.78 | TDP1 (0.43) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28052001 | 0.78 | TDP1 (0.43) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579444-A | Piperidinylindole derivatives and their use as complement factor B inhibitors | NOVARTIS AG | 2016-05-11 | — | — | CN | disclosed |