Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28312695 | 1.00 | TDP1 (0.43) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28052001 | 1.00 | TDP1 (0.43) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27992301 | 0.85 | TDP1 (0.45) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27767281 | 0.81 | TDP1 (0.38) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27724835 | 0.81 | TDP1 (0.48) | TDP1 | |
| SCHEMBL10261526 | 0.80 | — | — | |
| SCHEMBL10261945 | 0.80 | — | — | |
| SCHEMBL1360201 | 0.80 | — | — | |
| Tert-Butyl Formate SCHEMBL27853012 | 0.78 | TDP1 (0.35) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28064897 | 0.78 | PRCP (0.36) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110248936-A | Compound | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-110088103-A | Novel tetrahydropyridopyrimidine compounds for the treatment and prophylaxis of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-110003200-A | P2X7 regulator | 詹森药业有限公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-105209464-B | P2X7 modulators | 詹森药业有限公司 | 2019-01-01 | — | — | CN | disclosed |
| CN-105209464-A | P2x7 modulators | JANSSEN PHARMACEUTICA NV | 2015-12-30 | — | — | CN | disclosed |
| CN-105025899-A | Having a2AHeterobicyclically substituted- [1 ] with antagonist properties | MERCK SHARP & DOHME | 2015-11-04 | — | — | CN | disclosed |
| CN-104203928-A | Triazinone compound and T-type calcium channel inhibitor | NISSAN CHEMICAL IND LTD | 2014-12-10 | — | — | CN | disclosed |
| CN-102112467-B | Pyrimidine derivative as kinase inhibitors | IRM LLC | 2014-04-30 | — | — | CN | disclosed |
| CN-102498111-A | Sulfonamides as inhibitors of Bcl-2 family proteins for the treatment of cancer | NOVARTIS AG | 2012-06-13 | — | — | CN | disclosed |
| CN-102066337-A | 5-hydroxypyrimidine-4-carboxamide compounds | DAIICHI SANKYO CO LTD | 2011-05-18 | — | — | CN | disclosed |
| CN-101754962-A | N-azacyclic substituted pyrrole, imidazole, triazole and tetrazole derivatives as agonists of the RUP3 or GPR119 for the treatment of diabetes and metabolic disorders | METABOLEX INC | 2010-06-23 | — | — | CN | disclosed |
| CN-1777584-A | As 5-HT1F(Piperidyloxy) phenyl, (peridyloxy) pyridyl, (peridylthio) phenyl and (peridylthio) pyridyl compounds of agonists | LILLY CO ELI (US) | 2006-05-24 | — | — | CN | disclosed |