Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 5/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.34 |
| ▸ | CDK2 | P24941 | 5/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.34 |
| ▸ | CCNC | P24863 | 2/20 | 0.34 |
| ▸ | CDK8 | P49336 | 2/20 | 0.34 |
| ▸ | CLK1 | P49759 | 2/20 | 0.34 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.34 |
| ▸ | DMPK | Q09013 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.34 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401379 | 0.75 | RAB9A (0.39) | BAZ2APARP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28065021 | 0.75 | BAZ2A (0.40) | BAZ2AERCC1ERCC4CDC7CCNE1 | |
| SCHEMBL280241 | 0.72 | MKNK1 (0.31) | BAZ2AMKNK1 | |
| SCHEMBL5649233 | 0.71 | MKNK1 (0.40) | CDC7CCNE1CDK2ROCK1DBF4 | |
| SCHEMBL5649230 | 0.71 | MKNK1 (0.40) | CDC7CCNE1CDK2ROCK1DBF4 | |
| SCHEMBL259758 | 0.70 | MKNK1 (0.32) | BAZ2ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL263744 | 0.70 | MKNK1 (0.32) | BAZ2ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL18995321 | 0.69 | BAZ2A (0.34) | BAZ2AMKNK1 | |
| SCHEMBL10850350 | 0.68 | BAZ2A (0.37) | BAZ2AERCC1ERCC4PARP1 | |
| SCHEMBL873381 | 0.67 | PTGDR2 (0.53) | SLC6A3PTGDR2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579444-A | Piperidinylindole derivatives and their use as complement factor B inhibitors | NOVARTIS AG | 2016-05-11 | — | — | CN | disclosed |