Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15210 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL496907 | 0.95 | ALDH1A1 (0.36) | ALDH1A1 | |
| Bromide SCHEMBL9163595 | 0.95 | — | — | |
| Bromide SCHEMBL126528 | 0.95 | — | — | |
| Bromide SCHEMBL28177224 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL11434959 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL9482001 | 0.90 | ALDH1A1 (0.33) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28042039 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL28785215 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL28334257 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103154045-B | Copolymer and manufacture method thereof | BRIDGESTONE CO.,LTD. (JP) | 2016-05-11 | — | — | CN | disclosed |