Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.44 |
| ▸ | LIG1 | P18858 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16455153 | 1.00 | KDM1A (0.44) | KDM1ARCOR1LIG1CCR2PTGS2 | |
| SCHEMBL17984248 | 1.00 | KDM1A (0.44) | KDM1ARCOR1LIG1CCR2PTGS2 | |
| SCHEMBL15766923 | 0.83 | KDM1A (0.53) | KDM1AMAOAMAOB | |
| SCHEMBL14045495 | 0.83 | KDM1A (0.53) | KDM1AMAOAMAOB | |
| SCHEMBL13556691 | 0.83 | KDM1A (0.53) | KDM1AMAOAMAOB | |
| SCHEMBL3530324 | 0.83 | KDM1A (0.53) | KDM1AMAOAMAOB | |
| SCHEMBL15541000 | 0.83 | KDM1A (0.53) | KDM1AMAOAMAOB | |
| SCHEMBL8031930 | 0.82 | KDM1A (0.44) | KDM1ARCOR1LIG1RORCMAOA | |
| SCHEMBL4904346 | 0.78 | CYP11B2 (0.39) | KDM1A | |
| SCHEMBL28377204 | 0.78 | TDP1 (0.44) | RECQLNPSR1TDP1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105592888-A | Kdm1a inhibitors for the treatment of disease | IMAGO BIOSCIENCES INC | 2016-05-18 | — | — | CN | disclosed |