Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 1/20 | 0.72 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549240 | 0.83 | PANK3 (0.71) | PANK3TLR7HTR2CHPGDHDAC3 | |
| SCHEMBL28065290 | 0.81 | CYP1A2 (0.49) | PANK3LMNAHPGDCYP1A2CYP3A4 | |
| SCHEMBL27966313 | 0.81 | HIF1A (0.52) | PANK3LMNAHPGDCYP1A2CYP3A4 | |
| SCHEMBL3537090 | 0.80 | PANK3 (0.64) | PANK3TLR7HTR2CNPSR1L3MBTL1 | |
| SCHEMBL27966332 | 0.80 | HPGD (0.66) | TLR7LMNAHPGDCYP1A2CYP3A4 | |
| SCHEMBL3538271 | 0.79 | HTR2C (0.64) | PANK3TLR7HTR2CALDH1A1KDM4E | |
| SCHEMBL14716946 | 0.79 | PANK3 (0.62) | PANK3TLR7HTR2CLMNAHPGD | |
| SCHEMBL14662725 | 0.77 | CTSA (0.66) | PANK3TLR7 | |
| SCHEMBL14662722 | 0.77 | CTSA (0.66) | PANK3TLR7 | |
| SCHEMBL3539520 | 0.76 | HTR2C (0.64) | PANK3TLR7HTR2CKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103827098-B | The 3-(thiazole-4-carbonyl)-replaced or 3-(thiazole-2-carbonyl)-alanine derivatives and the purposes as medicine thereof | 赛诺菲 | 2016-06-15 | — | — | CN | claimed |
| CN-103827098-B | The 3-(thiazole-4-carbonyl)-replaced or 3-(thiazole-2-carbonyl)-alanine derivatives and the purposes as medicine thereof | 赛诺菲 | 2016-06-15 | — | — | CN | disclosed |