Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 1/20 | 0.71 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 5/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28065241 | 0.83 | PANK3 (0.72) | PANK3TLR7HPGDKDM4EALDH1A1 | |
| SCHEMBL7549244 | 0.81 | PANK3 (0.50) | PANK3TLR7KDM4EALDH1A1HTR2C | |
| SCHEMBL3537090 | 0.78 | PANK3 (0.64) | PANK3TLR7NPC1RAB9ANPSR1 | |
| SCHEMBL7549237 | 0.77 | PANK3 (0.50) | PANK3TLR7KDM4EALDH1A1HTR2C | |
| SCHEMBL13548679 | 0.75 | HTR2C (0.62) | PANK3TLR7NPC1RAB9AHTR2C | |
| SCHEMBL14716946 | 0.74 | PANK3 (0.62) | PANK3TLR7HPGDKDM4EALDH1A1 | |
| SCHEMBL15033595 | 0.74 | HPGD (0.55) | POLBHPGDKDM4EALDH1A1HTT | |
| SCHEMBL3538271 | 0.74 | HTR2C (0.64) | PANK3TLR7KDM4ENPC1ALDH1A1 | |
| SCHEMBL3539520 | 0.74 | HTR2C (0.64) | PANK3TLR7KDM4ENPC1RAB9A | |
| SCHEMBL31703693 | 0.73 | PANK3 (0.59) | PANK3TLR7HPGDKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237849-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2002-09-11 | — | — | EP | claimed |
| WO-2001032604-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2001-05-10 | — | — | WO | claimed |