SCHEMBL28065244

SCHEMBL28065244

c1c[nH]c(-c2cccc3c2ccc2ccccc23)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.52
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 4/20 0.44
TDP1 Q9NUW8 2/20 0.44
TSHR P16473 2/20 0.44
CYP2A6 P11509 1/20 0.44
KDM4E B2RXH2 1/20 0.42
ALPL P05186 1/20 0.42
GAA P10253 1/20 0.42
PAX8 Q06710 1/20 0.39
AURKA O14965 1/20 0.39
KDR P35968 1/20 0.39
HIF1A Q16665 3/20 0.39
CYP1A2 P05177 3/20 0.39
HPGD P15428 3/20 0.39
CYP1B1 Q16678 1/20 0.39
THRB P10828 1/20 0.39
MAPK1 P28482 3/20 0.39
LMNA P02545 2/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2289477 0.90 KDM4E (0.50) ALDH1A1HSD17B10TDP1TSHRCYP2A6
SCHEMBL30360255 0.90 ALDH1A1 (0.47) HPRT1ALDH1A1HSD17B10TDP1TSHR
SCHEMBL26259996 0.84 AURKA (0.48) KDM4EALPLGAAAURKAKDR
Pyridine SCHEMBL28095468 0.80 GSK3B (0.43) ALDH1A1HSD17B10TDP1TSHRKDM4E
SCHEMBL26259949 0.80 CDK2 (0.42) ALDH1A1HSD17B10AURKAKDRPARP1
SCHEMBL27947964 0.78 AURKA (0.39) ALDH1A1HSD17B10TSHRKDM4EALPL
SCHEMBL13562857 0.78 ALDH1A1 (0.42) ALDH1A1HSD17B10TDP1TSHRKDM4E
SCHEMBL29445992 0.77 HPRT1 (0.78) HPRT1ALDH1A1HSD17B10TDP1TSHR
SCHEMBL29769915 0.77 HPRT1 (0.78) HPRT1ALDH1A1HSD17B10TDP1TSHR
SCHEMBL593261 0.77 HPRT1 (0.78) HPRT1ALDH1A1HSD17B10TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113372289-A Organic electronic material containing phenanthrene azole compound and preparation method and application thereof 上海传勤新材料有限公司 2021-09-10 CN claimed
CN-105591033-A Organic Light-Emitting Device SAMSUNG DISPLAY CO LTD 2016-05-18 CN claimed
CN-112940008-B Organic electroluminescent material, preparation method thereof and organic electroluminescent device 吉林奥来德光电材料股份有限公司 2022-08-12 CN disclosed
CN-107710413-B Photoelectric conversion element, imaging element, multilayer imaging element, and imaging device 索尼公司 2022-01-14 CN disclosed
CN-113372289-A Organic electronic material containing phenanthrene azole compound and preparation method and application thereof 上海传勤新材料有限公司 2021-09-10 CN disclosed
CN-113372289-A Organic electronic material containing phenanthrene azole compound and preparation method and application thereof 上海传勤新材料有限公司 2021-09-10 CN disclosed
CN-113372289-A Organic electronic material containing phenanthrene azole compound and preparation method and application thereof 上海传勤新材料有限公司 2021-09-10 CN disclosed
CN-112940008-A Organic electroluminescent material, preparation method thereof and organic electroluminescent device 吉林奥来德光电材料股份有限公司 2021-06-11 CN disclosed
CN-105591033-A Organic Light-Emitting Device SAMSUNG DISPLAY CO LTD 2016-05-18 CN disclosed