Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21650439 | 0.79 | L3MBTL1 (0.47) | L3MBTL1HTTALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL11630698 | 0.78 | L3MBTL1 (0.46) | L3MBTL1HTTALDH1A1MAPTKDM4E | |
| SCHEMBL4109205 | 0.78 | L3MBTL1 (0.46) | L3MBTL1HTTALDH1A1MAPTKDM4E | |
| SCHEMBL10305720 | 0.77 | L3MBTL1 (0.44) | L3MBTL1HTTALDH1A1MAPTKDM4E | |
| SCHEMBL4104345 | 0.75 | L3MBTL1 (0.43) | L3MBTL1HTTALDH1A1MAPTKDM4E | |
| SCHEMBL28682071 | 0.74 | L3MBTL1 (0.42) | L3MBTL1HTTALDH1A1MAPTKDM4E | |
| SCHEMBL8869669 | 0.74 | L3MBTL1 (0.42) | L3MBTL1HTTALDH1A1MAPTKDM4E | |
| SCHEMBL7631548 | 0.72 | L3MBTL1 (0.41) | L3MBTL1HTTALDH1A1MAPTKDM4E | |
| SCHEMBL15055310 | 0.72 | L3MBTL1 (0.41) | L3MBTL1HTTALDH1A1MAPTKDM4E | |
| SCHEMBL9530715 | 0.72 | L3MBTL1 (0.41) | L3MBTL1HTTALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105593224-A | Novel quinazolinones as bromodomain inhibitors | ZENITH EPIGENETICS CORP | 2016-05-18 | — | — | CN | disclosed |