SCHEMBL28065452

SCHEMBL28065452

O=C(CC(O)C(=O)O)OCCOCCOCCO

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
TSHR P16473 3/20 0.37
MAPK1 P28482 1/20 0.37
OR51E2 Q9H255 1/20 0.37
TET2 Q6N021 3/20 0.35
TET3 O43151 1/20 0.35
TET1 Q8NFU7 1/20 0.35
EPHX2 P34913 1/20 0.33
ALDH1A1 P00352 2/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
HSD17B10 Q99714 1/20 0.31
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15282112 0.88 SMN1; SMN2 (0.46) SMN1; SMN2TSHROR51E2TET2TET3
SCHEMBL27714810 0.87 MEN1 (0.42) MEN1KMT2ATSHRMAPK1EPHX2
SCHEMBL7079361 0.84 SMN1; SMN2 (0.39) MEN1KMT2ASMN1; SMN2TSHROR51E2
SCHEMBL7079362 0.84 SMN1; SMN2 (0.39) MEN1KMT2ASMN1; SMN2TSHROR51E2
SCHEMBL9054036 0.84 ALDH1A1 (0.47) SMN1; SMN2TSHRTET2TET3TET1
SCHEMBL7079363 0.84 SMN1; SMN2 (0.39) MEN1KMT2ASMN1; SMN2TSHROR51E2
Triethylene Glycol SCHEMBL30580745 0.82 SMN1; SMN2 (0.62) MEN1KMT2ASMN1; SMN2TSHRMAPK1
Triethylene Glycol SCHEMBL28065453 0.82 SMN1; SMN2 (0.62) MEN1KMT2ASMN1; SMN2TSHRMAPK1
Ether SCHEMBL2962826 0.82 ALDH1A1 (0.39) SMN1; SMN2TSHROR51E2TET2TET3
Malic Acid SCHEMBL27714812 0.80 SMN1; SMN2 (0.65) MEN1KMT2ASMN1; SMN2TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102031529-B For the manufacture of the anticorrosive additive of process, Its Preparation Method And Use RHEIN CHEMIE RHEINAU GMBH (DE) 2016-05-18 CN disclosed