Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021591 | 1.00 | KMT2A (0.44) | KMT2AL3MBTL1GPR119MTNR1AMTNR1B | |
| SCHEMBL7020132 | 0.87 | KMT2A (0.51) | KMT2AL3MBTL1P2RX7HCRTR1HCRTR2 | |
| SCHEMBL28065531 | 0.87 | KMT2A (0.51) | KMT2AL3MBTL1P2RX7HCRTR1HCRTR2 | |
| SCHEMBL4870601 | 0.86 | KMT2A (0.59) | KMT2AMTNR1AMTNR1BBACE1P2RX7 | |
| SCHEMBL25408653 | 0.81 | GRM6 (0.43) | KMT2AMTNR1AMTNR1BP2RX7 | |
| SCHEMBL9095636 | 0.81 | GRM6 (0.43) | KMT2AMTNR1AMTNR1BP2RX7 | |
| SCHEMBL6745271 | 0.79 | KMT2A (0.44) | KMT2AL3MBTL1GPR119MTNR1AMTNR1B | |
| SCHEMBL6745269 | 0.79 | KMT2A (0.44) | KMT2AL3MBTL1GPR119MTNR1AMTNR1B | |
| SCHEMBL9352224 | 0.77 | KMT2A (0.56) | KMT2AL3MBTL1GPR119LMNAALDH1A1 | |
| SCHEMBL9356309 | 0.77 | KMT2A (0.56) | KMT2AL3MBTL1GPR119LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566447-B | The class peptide antagonists and its synthetic method of a kind of apoptosis inhibitory protein and application | 广东工业大学 | 2019-09-20 | — | — | CN | disclosed |
| CN-105566447-A | Peptoid antagonist of anti-apoptosis protein and synthesis method and application of peptoid antagonist | UNIV GUANGDONG TECHNOLOGY | 2016-05-11 | — | — | CN | disclosed |