Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | POLA1 | P09884 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745269 | 1.00 | KMT2A (0.44) | KMT2AL3MBTL1MTNR1AMTNR1BGPR119 | |
| SCHEMBL25405985 | 0.86 | MTNR1A (0.41) | KMT2AMTNR1AMTNR1BP2RX7 | |
| SCHEMBL25405978 | 0.86 | MTNR1A (0.41) | KMT2AMTNR1AMTNR1BP2RX7 | |
| SCHEMBL7020132 | 0.81 | KMT2A (0.51) | KMT2AL3MBTL1CYP3A4ALDH1A1P2RX7 | |
| SCHEMBL28065531 | 0.81 | KMT2A (0.51) | KMT2AL3MBTL1CYP3A4ALDH1A1P2RX7 | |
| SCHEMBL28065530 | 0.79 | KMT2A (0.44) | KMT2AL3MBTL1MTNR1AMTNR1BGPR119 | |
| SCHEMBL7021591 | 0.79 | KMT2A (0.44) | KMT2AL3MBTL1MTNR1AMTNR1BGPR119 | |
| SCHEMBL9352229 | 0.75 | KMT2A (0.55) | KMT2AL3MBTL1TRPM8CYP3A4KDM4E | |
| SCHEMBL9356309 | 0.74 | KMT2A (0.56) | KMT2AL3MBTL1GPR119TRPM8CYP3A4 | |
| SCHEMBL9352224 | 0.74 | KMT2A (0.56) | KMT2AL3MBTL1GPR119TRPM8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6685617-B1 | 4-(((-1-CARBOXY-2-(4-((2,6-DICHLOROBENZOYL)AMINE)PHENYL)ETHYL) AMINO)CARBONYL)-3-OXO-3-THIAZOLIDINEBUTANOIC ACID, USED AS ANTAGONISTS FOR CELLULAR ADHESION MOLECULES, AND ADMINISTERED AS ANTIINFLAMMATORY AGENTS | PHARMACIA & UPJOHN COMPANY | 2004-02-03 | — | — | US | disclosed |