SCHEMBL28065609

SCHEMBL28065609

CCNCCOCCCCC[Si](OC)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
CYP2C19 P33261 2/20 0.32
MEN1 O00255 1/20 0.32
GLA P06280 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP1A2 P05177 1/20 0.31
TSHR P16473 1/20 0.31
KDM1A O60341 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17707166 0.91 LMNA (0.35) LMNATSHR
SCHEMBL17706945 0.91 LMNA (0.35) LMNATSHR
SCHEMBL17707199 0.89 LMNA (0.32) LMNATSHR
SCHEMBL28828249 0.84 CYP2C19 (0.31) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL17706933 0.83 LMNA (0.33) LMNATSHR
SCHEMBL28065608 0.81 LMNA (0.34) LMNA
SCHEMBL6382948 0.81 CYP2C19 (0.50) LMNACYP2C19MEN1GLAKMT2A
SCHEMBL23152406 0.79 LMNA (0.55) LMNAMEN1KMT2ATSHRHTT
SCHEMBL57093 0.78 CYP2C19 (0.48) LMNACYP2C19MEN1GLAKMT2A
SCHEMBL20634245 0.78 CYP2C19 (0.52) CYP2C19MEN1GLAKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105566373-A Novel bisalkoxysilane compound and its production method SHINETSU CHEMICAL CO 2016-05-11 CN disclosed